Difference between revisions of "Team:UMaryland/Modeling"

<p>Kinetic parameters were obtained from the BRENDA enzyme database. there is no or only partial kinetic data available for some of the reactions in this pathway. Due to the lack of data our goal was do develop a framework which could used along with experimental data to construct an accurate model of carotenoid biosynthesis. Our aim is to use such a model to refine the production of specific products within the pathway by understanding how tuning different expression of different enzymes will impact the ratio and concentration of final products. Specifically, how tuning these enzymes will allow us to maximize alpha carotene production while minimizing unwanted derivatives.</p>

<p>Kinetic parameters were obtained from the BRENDA enzyme database. there is no or only partial kinetic data available for some of the reactions in this pathway. Due to the lack of data our goal was do develop a framework which could used along with experimental data to construct an accurate model of carotenoid biosynthesis. Our aim is to use such a model to refine the production of specific products within the pathway by understanding how tuning different expression of different enzymes will impact the ratio and concentration of final products. Specifically, how tuning these enzymes will allow us to maximize alpha carotene production while minimizing unwanted derivatives.</p>

<h3>In progress</h3>

<h3>In progress</h3>