Difference between revisions of "Team:Harvard BioDesign/Project"
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− | <section id="description" class="one dark cover"><header><h2> | + | <section id="description" class="one dark cover"><header><h2>Creating a New Tool</h2></header></section> |
+ | <img src="https://static.igem.org/mediawiki/2015/8/85/Harvard_2015_Project.png" alt="Project Logo" style="width:200px;height:200px;"/> | ||
+ | <h3> BactoGrip: The tool to advance science as we know it </h3> | ||
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Revision as of 13:37, 7 September 2015
Creating a New Tool
BactoGrip: The tool to advance science as we know it
About our project
Our team is engineering E. coli to bind to colon cancer cells through the use of their type I pili, which are hair-like appendages
that have an adhesive domain. Naturally, the strains in E. coli that produce pili bind to alpha-D-mannose, which can cause urinary tract infections.
However, our team is altering a non-harmful strain to produce pili using a modified Fim gene in order to localize the bacteria as a tool. For treatment of cancer,
once the bacteria are localized on the cells, the next step is to make them