Difference between revisions of "Team:Jilin China/Modeling"

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<h2> Modeling</h2>
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<h4>Note</h4>
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<img src="https://static.igem.org/mediawiki/2015/2/22/Team_Jilin_China_model1.png" height="750px"></div>
<p>In order to be considered for the <a href="https://2015.igem.org/Judging/Awards#SpecialPrizes">Best Model award</a>, you must fill out this page.</p>
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<p><big>As  the picture shows, higher the concentration of formaldehyde is, the later the  number of E.coli DH5αreach the lowest point. So  at first the high concentration may not beneficial to the growth of the  bacterias. But when they adapt to the high concentration, they can live longer  compared to those in the lower concentration. Therfore, E.coli&rsquo;s life span also  depend on formaldehyde concentration. But no matter what the concentration is,  E.coli will become inactive after 40 hours culturing.</big></p>
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<img src="https://static.igem.org/mediawiki/2015/5/5a/Team_Jilin_China_model2.png"height="645px"></div>
 
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<p><big>According to Fig.2, FDH and PADH indeed have a great effect on degrading formaldehyde. In the first 3h, the concentration of formaldehyde drops quickly. 32% formaldehyde gas has been absorbed. In the later 5 to 7 hours, the absorbing rate starts to be slower. Finally, these two enzymes degrade 42% formaldehyde.</big></p>
<p>Mathematical models and computer simulations provide a great way to describe the function and operation of BioBrick Parts and Devices. Synthetic Biology is an engineering discipline, and part of engineering is simulation and modeling to determine the behavior of your design before you build it. Designing and simulating can be iterated many times in a computer before moving to the lab. This award is for teams who build a model of their system and use it to inform system design or simulate expected behavior in conjunction with experiments in the wetlab.</p>
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Here are a few examples from previous teams:
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<li><a href="https://2014.igem.org/Team:ETH_Zurich/modeling/overview">ETH Zurich 2014</a></li>
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<li><a href="https://2014.igem.org/Team:Waterloo/Math_Book">Waterloo 2014</a></li>
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Revision as of 19:15, 16 September 2015



modeling

As the picture shows, higher the concentration of formaldehyde is, the later the number of E.coli DH5αreach the lowest point. So at first the high concentration may not beneficial to the growth of the bacterias. But when they adapt to the high concentration, they can live longer compared to those in the lower concentration. Therfore, E.coli’s life span also depend on formaldehyde concentration. But no matter what the concentration is, E.coli will become inactive after 40 hours culturing.

According to Fig.2, FDH and PADH indeed have a great effect on degrading formaldehyde. In the first 3h, the concentration of formaldehyde drops quickly. 32% formaldehyde gas has been absorbed. In the later 5 to 7 hours, the absorbing rate starts to be slower. Finally, these two enzymes degrade 42% formaldehyde.