Difference between revisions of "Team:Harvard BioDesign"

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<h1><center>Welcome to the Harvard BioDesign's 2015 Team Wiki!</center></h1>
 
<h1><center>Welcome to the Harvard BioDesign's 2015 Team Wiki!</center></h1>
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<p>Our team is engineering <i>E. Coli</i> to bind to colon cancer cells through the use of their type I pili, which are hair-like appendages
 
<p>Our team is engineering <i>E. Coli</i> to bind to colon cancer cells through the use of their type I pili, which are hair-like appendages
 
that have an adhesive domain. Naturally, the strains in <i>E. coli</i> that produce pili bind to alpha-D-mannose, which can cause urinary track infections.
 
that have an adhesive domain. Naturally, the strains in <i>E. coli</i> that produce pili bind to alpha-D-mannose, which can cause urinary track infections.
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once the bacteria are localized on the cells, the next step is to make the <E. coli</i> capable of producing a concentrated toxin or to administer a therapeutic.
 
once the bacteria are localized on the cells, the next step is to make the <E. coli</i> capable of producing a concentrated toxin or to administer a therapeutic.
 
Other potential applications for our <i>E. coli </i> include water pollution clean up through methods such as flocculation and targeting areas through GFP.</p>  
 
Other potential applications for our <i>E. coli </i> include water pollution clean up through methods such as flocculation and targeting areas through GFP.</p>  
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Revision as of 04:01, 15 July 2015

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Welcome to the Harvard BioDesign's 2015 Team Wiki!

Our team is engineering E. Coli to bind to colon cancer cells through the use of their type I pili, which are hair-like appendages that have an adhesive domain. Naturally, the strains in E. coli that produce pili bind to alpha-D-mannose, which can cause urinary track infections. However, our team is altering a non-harmful strain to produce pili using a modified Fim gene in order to localize the bacteria as a tool. For treatment of cancer, once the bacteria are localized on the cells, the next step is to make the capable of producing a concentrated toxin or to administer a therapeutic. Other potential applications for our E. coli include water pollution clean up through methods such as flocculation and targeting areas through GFP.