Difference between revisions of "Team:China Tongji/Safety"

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<!--content start-->
 
<!--content start-->
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<div class="bigName">
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<p align="left">Safety</p>
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<div class="myContent">
 
<div class="myContent">
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<div id="contentList">
 
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        <li class="listOne"><p id="listProjectDesign">Project Design</p></li>
 
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        <li class="listOne"><p id="listLabWork">Lab Work</p></li>
 
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        <li class="listOne"><p id="listShipment">Shipment</p></li>
 
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     <div id=mainContent>
 
     <div id=mainContent>
 
     <!-- maincontent start here -->
 
     <!-- maincontent start here -->
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         <p class="titleOne" id="ProjectDesign">1. Project Design</p>  
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         <div class="titleOneBlock">
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        <p class="contentP">
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        <div class="titleButton"><a id="buttonProject" href="https://2015.igem.org/Team:China_Tongji/Project">Project</a></div>
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        Cells sense the environment, process information, and make response to stimuli. To make cells work well in complex natural environments, lots of processes have to be preset to react to various signals. However, when well-characterized modules are combined to construct higher order systems, unpredictable behaviors often occur because of the interplay between modules. Another significant problem is that complex integrated systems composed of numerous parts may cause cell overload.</p>
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          <div class="titleButton"><a id="buttonNotebook" href="https://2015.igem.org/Team:China_Tongji/Notebook">Notebook</a></div>
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          <div class="titleButton"><a id="buttonAchivement" href="https://2015.igem.org/Team:China_Tongji/Achivement">Achivement</a></div>
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         <p class="imgName" align="center">Figure 1. Schematic demonstration of HIV</p>
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          <div class="titleButton"><a id="buttonOutreach" href="https://2015.igem.org/Team:China_Tongji/Outreach">Outreach</a></div>
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         <p class="contentP">
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          <div class="titleButton"><a id="buttonSafety" href="https://2015.igem.org/Team:China_Tongji/Safety">Safety</a></div>
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        We proposed an elegant method to design higher order systems. Instead of merely combining different functional modules, we constructed one integrated processing module with fewer parts by utilizing the common structures between modules. The circuit we designed is a rewirable one and the topological structure of the processing module can be altered to <span style="font-weight:bold;">adapt</span> to environmental change. The basic idea is to rewire the connections between parts and devices to <span style="font-weight:bold;">implement multiple functions</span> with the help of the site-specific recombination systems.</p>
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         </div>
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        <p class="contentP">
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        Our design approach may lead to a revolutionary step towards <span style="font-weight:bold;">system integration</span> in synthetic biology. Potential fields of application include organism development, living therapeutics and environment improvement.</p>
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        <div class="dividerNone"></div>
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         <p></p><div class="divider"></div>
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    <p class="titleOne" id="ProjectIntroduction">Project Introduction</p>  
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         <div class="divider"></div>
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    <p class="contentP">In our project, we will use the technology of optogenetic and use light of different wave produced by the special light source assembled by ourselves to control the moving of C.elegans, construct a movement controlling system and bulid an amusement park of C.elegans.</p>
 +
<p class="contentP">We will try to design our special parts and express channalrhodopsin in specific C.elegans' neurons. To accomplish our goals to express channalrhodopsin in single neuron, we make the use of cre- loxp system and the overlapping of promoters. We not only use the traditional channalrhodopsin,chR2,but also try to express the novel channelrhodopsin, Blink, and other fancy channelrhodopsins which have never been tested in C.elegans.</p>
 +
<p class="contentP">And we will also get some parts and assemble those parts into a new equipment which can serves as the light source of our experiment.Then we will use computer controlling that lightsource to change the light which can activate or suppress the channelrhodopsin. By doing that, we can try to control the behaviours of C.elegans such as moving forwards or twisting more effectively.</p>
 +
<p class="contentP">What's more,we will express GFP,YFP,mcherry in E.coli. By combining the color of microorgasims and C.elegans, we want to construct some interesting scenes to form a C.elegans' fancy world.</p>
 +
<p class="contentP">This technology will be helpful in the research on neuron's function and interaction. In the future, this technology may also be used in mechanical controlling system and the theraphy of movement defect.</p>
 +
         <div class="divider"></div>
 +
       
 +
    <p class="titleOne" id="VideoAppreciation">Video Appreciation</p>  
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  <div class="videoWrapper">
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            <video controls width="990">
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                <source src="https://static.igem.org/mediawiki/2015/3/36/Tongji_University_promotional_video_2011.mp4" type="video/mp4" />Your browser does not support the video tag.
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            </video>
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  </div>      
 
          
 
          
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        <p class="titleOne" id="LabWork">2. Lab Work</p>
 
−
        <p class="contentP">
 
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        Cells sense the environment, process information, and make response to stimuli. To make cells work well in complex natural environments, lots of processes have to be preset to react to various signals. However, when well-characterized modules are combined to construct higher order systems, unpredictable behaviors often occur because of the interplay between modules. Another significant problem is that complex integrated systems composed of numerous parts may cause cell overload.</p>
 
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        <center><img class="contentImg" src="https://static.igem.org/mediawiki/2015/2/20/China_Tongji_iGEM_logo.png" ></center>
 
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        <p class="imgName" align="center">Figure 2. China_Tongji_iGEM_logo</p>
 
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        <p class="contentP">
 
−
        Our design approach may lead to a revolutionary step towards <span style="font-weight:bold;">system integration</span> in synthetic biology. Potential fields of application include organism development, living therapeutics and environment improvement.</p>
 
−
        <p></p><div class="divider"></div>       
 
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<p class="titleOne" id="Shipment">3. Shipment</p> 
 
−
        <p class="contentP">
 
−
        Cells sense the environment, process information, and make response to stimuli. To make cells work well in complex natural environments, lots of processes have to be preset to react to various signals. However, when well-characterized modules are combined to construct higher order systems, unpredictable behaviors often occur because of the interplay between modules. Another significant problem is that complex integrated systems composed of numerous parts may cause cell overload.</p>
 
−
        <center><img class="contentImg" src="https://static.igem.org/mediawiki/2015/2/20/China_Tongji_iGEM_logo.png" ></center>
 
−
        <p class="imgName" align="center">Figure 2. China_Tongji_iGEM_logo</p>
 
−
        <p class="contentP">
 
−
        Our design approach may lead to a revolutionary step towards <span style="font-weight:bold;">system integration</span> in synthetic biology. Potential fields of application include organism development, living therapeutics and environment improvement.</p>
 
 
    
 
    
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Revision as of 10:56, 5 August 2015

Project
Notebook
Achivement
Outreach
Safety

Project Introduction

In our project, we will use the technology of optogenetic and use light of different wave produced by the special light source assembled by ourselves to control the moving of C.elegans, construct a movement controlling system and bulid an amusement park of C.elegans.

We will try to design our special parts and express channalrhodopsin in specific C.elegans' neurons. To accomplish our goals to express channalrhodopsin in single neuron, we make the use of cre- loxp system and the overlapping of promoters. We not only use the traditional channalrhodopsin,chR2,but also try to express the novel channelrhodopsin, Blink, and other fancy channelrhodopsins which have never been tested in C.elegans.

And we will also get some parts and assemble those parts into a new equipment which can serves as the light source of our experiment.Then we will use computer controlling that lightsource to change the light which can activate or suppress the channelrhodopsin. By doing that, we can try to control the behaviours of C.elegans such as moving forwards or twisting more effectively.

What's more,we will express GFP,YFP,mcherry in E.coli. By combining the color of microorgasims and C.elegans, we want to construct some interesting scenes to form a C.elegans' fancy world.

This technology will be helpful in the research on neuron's function and interaction. In the future, this technology may also be used in mechanical controlling system and the theraphy of movement defect.

Video Appreciation

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