Team:SJTU-BioX-Shanghai/Modeling

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Modeling

Introduction

Overview

This report is trying to give a qualitative description of our team’s desalination tool. Before we enter the modelling part of this report, I want to give some basic ideas of our team’s project and some mathematical tools I will use during the modelling. Our team’s project focuses on the worldwide problem-shortage of fresh water. We try to modify the cyanobacterium via the methods and tools of biosynthesis. We want to im-plant the Natronomonas pharaonis halorhodopsin(pHR), which is an archaeal rhodopsin functioning as an inward-directed, lightdriven Cl − pump, into the cyanobacterium. We want to use this protein carried by cyanobacterium and driven by light energy to desalinate the sea water. That’s the very general idea of our project. At the meantime, we modify the corresponding promoter of pHR which makes the expression of pHR inhibited in dark environment. Such a promoter is just like a switch which could control the expression of pHR by the environment. Then, the whole working landscape of our modified cyanobacterium could be divided as following steps:

  1. Natural Growth
  2. Dark Expression
  3. Starving Working

I will explain each process in detail in the following sections.

Modeling

Simulation

Conclusion

References

Natural Growth Process

Dark Expression Process