Modeling

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Our main goal is to make a reproducible biofilm. The strength of the biofilm is determined by the degree of intercellular connectivity through curli fibers. With modeling, it is possible to determine which factors have a strong influence on the intercellular connectivity. For instance, one could argue that a higher csgB nucleator production would lead to more curli fibers and therefore an improved connectivity. But if the csgA production would be limiting, solely short curli chains would be formed possibly preventing the cells to even interconnect.

Gene Modeling

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