Team:Dundee/Part Collection

The Building Blocks of Our Project

Part Collection

Part: BBa_K1590000 (hHBA)

FluID- Blood Detection

Coding sequence for Human haemoglobin A. Haemoglobin is the tetrameric protein molecule in red blood cells that carries oxygen. It is composed of four polypeptide chains, which in adults consist of two alpha (a) globin chains and two beta (b) globin chains. In blood plasma, haptoglobin binds free haemoglobin released from red blood cells, inhibiting its oxidative activity. The haptoglobin-hemoglobin complex can then be removed by the reticuloendothelial system which is a part of the immune system. Despite this, haemoglobin is still found free in the blood plasma at a concentration of up to 0.1g/l and this is what we hope to detect.

Figure 1 - This figure illustrates the relationship between fingertip, substrate and environmental conditions which collectively form a fingerprint and its constituents.