Difference between revisions of "Team:METU Turkey/Design"

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{{METU_Turkey}}
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<h2>Design</h2>
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By talking about your design work on this page, there is one medal criterion that you can attempt to meet, and one award that you can apply for. If your team is going for a gold medal by building a functional prototype, you should tell us what you did on this page. If you are going for the <a href="https://2015.igem.org/Judging/Awards#SpecialPrizes">Applied Design award</a>, you should also complete this page and tell us what you did.  
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</head>
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<body>
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    <ul class="nav">
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        <li>
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            <a class="one" href="https://2015.igem.org/Team:METU_Turkey">Home</a>
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        </li>
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        <li>
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            <a class="one" href="https://2015.igem.org/Team:METU_Turkey/Team">Team</a>
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        </li>
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                <li>
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            <a class="one" href="https://2015.igem.org/Team:METU_Turkey/Description">Project</a>
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            <ul>
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                <li><a href="https://2015.igem.org/Team:METU_Turkey/Experiments">Experiments</a></li>
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                <li><a href="https://2015.igem.org/Team:METU_Turkey/Results">Results</a></li>
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                <li><a href="https://2015.igem.org/Team:METU_Turkey/Design">Design</a></li>
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            </ul>
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        </li>
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        <li>
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            <a class="one" href="https://2015.igem.org/Team:METU_Turkey/Parts">Parts</a>
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            <ul>
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                <li><a href="https://2015.igem.org/Team:METU_Turkey/Basic_Part">Basic Part</a></li>
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                <li><a href="https://2015.igem.org/Team:METU_Turkey/Composite_Part">Composite Part</a></li>
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                <li><a href="https://2015.igem.org/Team:METU_Turkey/Part_Collection">Part Collection</a></li>
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            </ul>
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            </li>
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        <li>
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            <a class="one" href="https://2015.igem.org/Team:METU_Turkey/Notebook">Notebook</a>
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        </li>
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        <li>
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            <a class="one" href="https://2015.igem.org/Team:METU_Turkey/Attributions">Attributions</a>
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        </li>
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        <li>
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            <a class="one" href="https://2015.igem.org/Team:METU_Turkey/interlab">Interlab</a>
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        </li>
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        <li>
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            <a class="one" href="https://2015.igem.org/Team:METU_Turkey/Collaborations">Collaborations</a>
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        </li>
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        <li>
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            <a class="one" href="https://2015.igem.org/Team:METU_Turkey/Practices">Human Practices</a>
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        </li>
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        <li>
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            <a class="one" href="https://2015.igem.org/Team:METU_Turkey/Safety">Safety</a>
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        </li>
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        <li>
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            <a class="one" href="https://2015.igem.org/Team:METU_Turkey/Gallery">Gallery</a>
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        </li>
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        <li>
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            <a class="one" href="https://2015.igem.org/Team:METU_Turkey/Sponsors">Sponsors</a>
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        </li>
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        </li>
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    </ul>
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<!-- First block of content -->
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<table  cellspacing="20px" height="150px" align="center">
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<tr>
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<td align="center" width="350px"><a href="https://igem.org/Main_Page" target="_blank"> <img src="https://static.igem.org/mediawiki/igem.org/6/60/Igemlogo_300px.png" width="150px"></a></td>
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<td align="center" bgColor="#FFFFFF" >
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<!-- You can replace this image with your team's logo! -->
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<img src="https://static.igem.org/mediawiki/2014/c/cc/Metuigem_logo.png" width="120px">
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<h3>Welcome!  <br> We are Team METU_Turkey! </h3>
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</td>
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<td align="center" width="162px"><a href="http://www.metu.edu.tr"color:#FFFFFF" target="_blank"><img src="https://static.igem.org/mediawiki/2014/9/91/Metulogo.jpg" width="300px"></a></td>
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</table>
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<table>
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<h4 align=center>Project Circuit</h4>
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<tr>
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<img hspace="375px" align=center src="https://static.igem.org/mediawiki/2015/6/6a/K1606007.PNG" width="600px">
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<img hspace="375px" align=center src="https://static.igem.org/mediawiki/2015/f/fb/K1606010.PNG" width="600px">
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<img hspace="375px" align=center src="https://static.igem.org/mediawiki/2015/f/f9/K1606029.PNG" width="600px">
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</tr>
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<tr>
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<div class="highlightBox">
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<p align=center>We modernized m-cherry (BBa_J06504) part to report the absence of the gluten protein in a solution or in a dough that our updated Kumamax enzyme is inactive in the environment. When the absence of the protein of the gluten our repoter gene is expressed and give red light to environment. Besides LacI promoter works under acidic environment in the dough formation.
 
</p>
 
</p>
  
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<tr>
 
<div class="highlightBox">
 
<div class="highlightBox">
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<h4>Note</h4>
 
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<p>In order to be considered for the <a href="https://2015.igem.org/Judging/Awards#SpecialPrizes">Best Applied Design award</a> and/or the <a href="https://2015.igem.org/Judging/Awards#Medals">functional prototype gold medal criterion</a>, you must fill out this page.</p>
 
 
</div>
 
</div>
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</tr>
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</table>
  
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<p>This is a prize for the team that has developed a synthetic biology product to solve a real world problem in the most elegant way. The students will have considered how well the product addresses the problem versus other potential solutions, how the product integrates or disrupts other products and processes, and how its lifecycle can more broadly impact our lives and environments in positive and negative ways.</p>
 
  
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<p>
 
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If you are working on art and design as your main project, please join the art and design track. If you are integrating art and design into the core of your main project, please apply for the award by completing this page.
 
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</p>
 
  
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<table>
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<h4 align=center>Kill Switch Circuit</h4>
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<tr>
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<img hspace="375px" align=center src="https://static.igem.org/mediawiki/2015/7/7d/K1606014.PNG" width="600px">
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</tr>
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<tr>
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<div class="highlightBox">
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<p align=center>Strong promoter without thickener of LuxR and antiholin sequence:
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For our kill switch model first we design a circuit that secrete antiholin LuxR gene to supress the activity of holin and endolysin enzymes for working under normal conditions by digesting gluten into its small particles. After this composite part we design a new circuit that our composite gene part secrete a thickener(Xanthan Gum) that dough doesn't lose its stability and viscose structure type for consumers' choice.
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</p>
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<hr>
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<tr>
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<img hspace="375px" align=center src="https://static.igem.org/mediawiki/2015/5/56/K1606020.PNG" width="600px">
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</tr>
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<tr>
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<div class="highlightBox">
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<p align=center>Lux promoter activated by thickener(Xanthan Gum) gene part of LuxR and it start to lyse the cell with holin and endolysin activity.
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</p>
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<tr>
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<tr>
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<div class="highlightBox">
 
</div>
 
</div>
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</tr>
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</table>
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<!-- Sponsorlar beginning -->
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    <table  id="firstblock" width="60%"  cellspacing="10px" height="200px" align="center">
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        <tr>
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        <td align=center>
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<a href="http://www.metu.edu.tr" target="_blank"> <img src="https://static.igem.org/mediawiki/2014/9/91/Metulogo.jpg" width="350px" align="center"></a>
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        </td>
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        </tr>
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    </table>
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<table  id="firstblock" width="60%"  cellspacing="10px" height="200px" align="center">
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<tr>
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<td align="center" width="162px"><a href="http://odtuteknokent.com.tr/" target="_blank"> <img src="https://static.igem.org/mediawiki/2014/4/47/Odtuteknokent.jpg" width="175px"></a></td>
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<td align="center" width="162px"><a href="http://www.kardiosis.com.tr/" target="_blank"> <img src="https://static.igem.org/mediawiki/2014/d/d4/Kardiosis.jpg" width="175px"></a></td>
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<td align="center" width="162px"><a href="http://www.tr-idea.com/" target="_blank"> <img src="https://static.igem.org/mediawiki/2015/c/c6/METU_Turkey_Idea.PNG" width="350px"></a></td>
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</tr>
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</table>
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<table align="center" cellspacing="10px">
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<tr>
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<td align="center"><a href="http://www.sentegen.com/" target="_blank"> <img src="https://static.igem.org/mediawiki/2014/d/dd/Sentegenlogoder.PNG" width="175px"></a></td>
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<td align="center"><a href="http://www.mathworks.com/" target="_blank"> <img src="https://static.igem.org/mediawiki/2015/a/ab/METU_Turkey_mathworks.png" width="175px"></a></td>
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</tr>
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</table>
  
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<!-- Sponsorlar end -->
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</body>
 
</html>
 
</html>

Latest revision as of 13:29, 4 October 2015

Welcome!
We are Team METU_Turkey!

Project Circuit

We modernized m-cherry (BBa_J06504) part to report the absence of the gluten protein in a solution or in a dough that our updated Kumamax enzyme is inactive in the environment. When the absence of the protein of the gluten our repoter gene is expressed and give red light to environment. Besides LacI promoter works under acidic environment in the dough formation.

Kill Switch Circuit

Strong promoter without thickener of LuxR and antiholin sequence: For our kill switch model first we design a circuit that secrete antiholin LuxR gene to supress the activity of holin and endolysin enzymes for working under normal conditions by digesting gluten into its small particles. After this composite part we design a new circuit that our composite gene part secrete a thickener(Xanthan Gum) that dough doesn't lose its stability and viscose structure type for consumers' choice.

Lux promoter activated by thickener(Xanthan Gum) gene part of LuxR and it start to lyse the cell with holin and endolysin activity.