Difference between revisions of "Team:William and Mary"

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                                                 <p>As synthetic biology begins to construct increasingly complex gene regulatory networks, the need for accurate quantitative characterization of regulatory components becomes more pressing. Despite the extensive characterization of the average strength of the promoters available on the BioBrick registry, very few have information pertaining to the variability in their expression. Our project aims to characterize this variability, commonly referred to as stochasticity, or noise, in gene expression, for the most commonly used promoters in synthetic biology and provide additional tools for the regulation of these promoters.  
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                                                 <p>As synthetic biologists begin to construct increasingly complex gene regulatory networks, the need for accurate quantitative characterization of regulatory components becomes more pressing. Despite the extensive characterization of the average strength of the promoters available on the BioBrick registry, very few have information pertaining to the variability in their expression. Our project aims to characterize this variability, commonly referred to as stochasticity, or noise, in gene expression, for the most commonly used promoters in synthetic biology and provide additional tools for the regulation of these promoters.  
 
                                                 <p><a href="https://2015.igem.org/Team:William_and_Mary/Description">Read more on our Project Description page.</a>
 
                                                 <p><a href="https://2015.igem.org/Team:William_and_Mary/Description">Read more on our Project Description page.</a>
 
                                                 </p>
 
                                                 </p>

Revision as of 03:31, 18 September 2015

NOISE - W&M iGEM

NOISE

Characterization of promoter-derived transcriptional noise in E. coli

Measurement & Modeling

talk a lil about stuff we measured/math model here. 4 components of math model (each will have an icon: Data, analysis, another model, case study)

Data

integrated/plasmid

analysis

parameters and stuff.

Another Model

explain from where

Case Study

applying our model to someone else's stuff

Human Practices

Our Human Practices effort was a multi-faceted outreach approach to science literacy, focusing specifically on spreading a basic understanding of synthetic biology to the general public. We collaborated with numerous organizations (logos below) to host nine educational Synthetic Biology workshops for the public (from first graders to adults!) and to implement our original, 24-activity Synthetic Biology curriculum into schools worldwide, to further sustain our efforts for years to come.

Collaboration

W&M iGEM met and exceeded iGEM's collaboration requirements by collaborating with other researchers in four main ways: creating a pen pal program to connect teams with similar projects, participating in the interlab measurement study, interviewing the general public to provide data to future teams about how to communicate synthetic biology, and collaborating on individual research projects with iGEM teams from University of Georgia, University of Maryland, and Cambridge.

Team

Noise, one promoter at a time.

...