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| − | <h1>Collaborations<small> Working together!<small></h1> | + | <h1>Collaboration<small> Working across the Atlantic<small></h1> |
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| | <a href="https://2015.igem.org/Stanford-Brown/Vision"> | | <a href="https://2015.igem.org/Stanford-Brown/Vision"> |
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| − | <h2 class="featurette-heading">Our Vision<span class="small"> to create biological origami aka BiOrigami</span></h2> | + | <h2 class="featurette-heading">Collaboration<span class="small"> with the University of Edinburgh</span></h2> |
| − | <p class="lead">Donec ullamcorper nulla non metus auctor fringilla. Vestibulum id ligula porta felis euismod semper. Praesent commodo cursus magna, vel scelerisque nisl consectetur. Fusce dapibus, tellus ac cursus commodo.</p> | + | <p class="lead">The University of Edinburgh iGEM 2015 team is creating a paper-based biosensor to detect purity of and contaminants in illicit drugs. In an effort to increase the applications of the proof-of-concept biosensor, the team wanted to incorporate microbial cellulose as an alternative to filter paper. This could decrease the cost of the biosensor as well as making the disposal easier. By using microbial cellulose that our team provided, the University of Edinburgh team was able to check the binding affinities of a cellulose binding domain (CBD) to the cellulose to see whether microbial cellulose-based biosensors are feasible. Our bioHYDRA project involved testing processed and unprocessed cellulose, and we sent the Edinburgh team a sample of each. This allowed the Edinburgh team to see if there is an advantage to the processing for their applications, and, since our future work includes expressing CBDs on spore coats, the processed sheets will be better for our applications as well. The data (see figure) shows that less protein dissociation occurred from the processed sheets. |
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| − | <h2 class="featurette-heading">But how? <span class="small"> with the following projects below</span></h2>
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| − | <p class="lead">Based on work done by Chen et al. at Columbia university, we sought to employ the contractile properties of bacterial spores to use as a contractile mechanism for biOrigami.</p>
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