Difference between revisions of "Team:Freiburg/Home"
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<div class="cool_header"><a href='#'>Own Device</a></div> | <div class="cool_header"><a href='#'>Own Device</a></div> | ||
<div class="cool_image_blink element1"> | <div class="cool_image_blink element1"> | ||
− | <div class="cool_content cool_text_blink"> | + | <div class="cool_content cool_text_blink">We built our own simplified and affordable detection device. Check out the step by step instructions !</div> |
</div> | </div> | ||
</li> | </li> | ||
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<div class="cool_header"><a href='#'>New iGEM Backbone</a></div> | <div class="cool_header"><a href='#'>New iGEM Backbone</a></div> | ||
<div class="cool_image_blink element2"> | <div class="cool_image_blink element2"> | ||
− | <div class="cool_content cool_text_blink"> | + | <div class="cool_content cool_text_blink">We provided a new backbone for protein overexpression meeting all the iGEM standards. <br> See how we epanded the iGEM registry!</div> |
</div> | </div> | ||
</li> | </li> | ||
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<div class="cool_header"><a href='#'>Human Practice</a></div> | <div class="cool_header"><a href='#'>Human Practice</a></div> | ||
<div class="cool_image_blink element3"> | <div class="cool_image_blink element3"> | ||
− | <div class="cool_content cool_text_blink">What | + | <div class="cool_content cool_text_blink">What do people think about the DiaCHIP and systems based on synthetic biology? <br> Check out the results of our survey and discussions !</div> |
</div> | </div> | ||
</li> | </li> | ||
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<div class="cool_header"><a href='#'>Modeling</a></div> | <div class="cool_header"><a href='#'>Modeling</a></div> | ||
<div class="cool_image_blink element4"> | <div class="cool_image_blink element4"> | ||
− | <div class="cool_content cool_text_blink"> | + | <div class="cool_content cool_text_blink">Modeling the generation of proteins during cell-free expression as well as their diffusion in our system helped us obtaining better results. Get more information here.</div> |
</div> | </div> | ||
</li> | </li> | ||
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<div class="cool_header"><a href='#'>Blood Serum Analysis</a></div> | <div class="cool_header"><a href='#'>Blood Serum Analysis</a></div> | ||
<div class="cool_image_blink element5"> | <div class="cool_image_blink element5"> | ||
− | <div class="cool_content cool_text_blink">We | + | <div class="cool_content cool_text_blink">We successfully detected tetanus antibodies in human blood serum and measured binding of GFP antibodies to cell-free expressed GFP. <br> Visit our results page !</div> |
</div> | </div> | ||
</li> | </li> | ||
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<li><!--6--> | <li><!--6--> | ||
− | <div class="cool_header"><a href='#'> | + | <div class="cool_header"><a href='#'>Diagnostics today</a></div> |
<div class="cool_image_blink element6"> | <div class="cool_image_blink element6"> | ||
− | <div class="cool_content cool_text_blink"> | + | <div class="cool_content cool_text_blink">Nowadays, medical diagnosis is mainly based on huge amounts of time-consuming and costly serological tests. |
− | + | Read more about the issues we tackled !</div> | |
</div> | </div> | ||
</li> | </li> | ||
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<div class="cool_header"><a href='#'>The DiaCHIP</a></div> | <div class="cool_header"><a href='#'>The DiaCHIP</a></div> | ||
<div class="cool_image_blink element7"> | <div class="cool_image_blink element7"> | ||
− | <div class="cool_content cool_text_blink">Simultaneously screening for hundreds of diseases within a few hours? | + | <div class="cool_content cool_text_blink">Simultaneously screening for hundreds of diseases within a few hours? <br> Find out about the DiaCHIP's potential to revolutionize future diagnostics !</div> |
</div> | </div> | ||
</li> | </li> | ||
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<div class="cool_header"><a href='#'>Our System</a></div> | <div class="cool_header"><a href='#'>Our System</a></div> | ||
<div class="cool_image_blink element8"> | <div class="cool_image_blink element8"> | ||
− | <div class="cool_content cool_text_blink">Generating a protein array on demand and detecting antigen-antibody interactions in real-time: | + | <div class="cool_content cool_text_blink">Generating a protein array on demand via cell-free expression and detecting antigen-antibody interactions label-free and in real-time: The principle behind the DiaCHIP !</div> |
</div> | </div> | ||
</li> | </li> |
Revision as of 11:36, 13 September 2015
![](https://static.igem.org/mediawiki/2015/8/85/Freiburg_wiki_background_2_parted_left.png)
![](https://static.igem.org/mediawiki/2015/f/f4/Freiburg_wiki_background_2_parted_right.png)
-
We built our own simplified and affordable detection device. Check out the step by step instructions !
-
We provided a new backbone for protein overexpression meeting all the iGEM standards.
See how we epanded the iGEM registry! -
What do people think about the DiaCHIP and systems based on synthetic biology?
Check out the results of our survey and discussions ! -
Modeling the generation of proteins during cell-free expression as well as their diffusion in our system helped us obtaining better results. Get more information here.
-
We successfully detected tetanus antibodies in human blood serum and measured binding of GFP antibodies to cell-free expressed GFP.
Visit our results page ! -
Nowadays, medical diagnosis is mainly based on huge amounts of time-consuming and costly serological tests. Read more about the issues we tackled !
-
Simultaneously screening for hundreds of diseases within a few hours?
Find out about the DiaCHIP's potential to revolutionize future diagnostics ! -
Generating a protein array on demand via cell-free expression and detecting antigen-antibody interactions label-free and in real-time: The principle behind the DiaCHIP !
![](https://static.igem.org/mediawiki/2015/9/91/Freiburg_homepage_Dia_chip.png)
DiaCHIP - Enlightening Diagnostics
In modern medicine, fast detection and differentiation of diseases is a crucial and fundamental task. Typical ELISA-based assays are time-consuming and expensive. We propose an advanced procedure for the simultaneous detection of various diseases in a fast and inexpensive manner, the DiaCHIP. Our approach is based on the interaction of antibodies with their respective antigens. Different antigens are immobilized on a protein array generated by cell-free protein expression, using the corresponding DNA array as a template. Placed in a microfluidic chamber, the protein array is incubated with a patient’s blood sample. The interaction between an antibody in the sample and the corresponding immobilized antigen results in a local change of the optical thickness of the surface. This change can be detected using a label-free and real-time measurement technology called iRIf (imaging Reflectometric Interference). Offering simultaneous screening for several diseases, our DiaCHIP has strong potential to improve future diagnostics.