Difference between revisions of "Team:Northeastern Boston/Collaborations"

 
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        <a href="https://2015.igem.org/Team:Northeastern_Boston/Practices">Human Practices</a>
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  <h1 class="page-header__title" align="left" style="border-width:0;color:white">COLLABORATION</h1>
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    <h1 id="project_header" style="border-width:0">COLLABORATION</h1>
 
  
 
<h2><a href="https://static.igem.org/mediawiki/2015/e/e9/Collaboration_Brochure_FINAL.pdf" target="_blank" style="color:#7CAAD9">Handbook for non-model iGEM organisms</a></h2>
 
<h2><a href="https://static.igem.org/mediawiki/2015/e/e9/Collaboration_Brochure_FINAL.pdf" target="_blank" style="color:#7CAAD9">Handbook for non-model iGEM organisms</a></h2>
  
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<p>Despite <i>Chlamydomonas reinhardtii</i> being a model organism in the world of microalgae research, its presence at iGEM has been virtually non-existent. With a few exceptions like <a href="https://2014.igem.org/Team:Concordia" target="_blank">Concordia 2014</a> and <a href="https://2012.igem.org/Team:Valencia" target="_blank">Valencia 2012</a>, microalgae has made little of an appearance. While we hope our protein expression plasmid makes it easier for future teams to use <i>Chlamydomonas reinhardtii</i>, we went further by contributing to a dedicated non-model organisms</p>
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<p>Despite <i>Chlamydomonas reinhardtii</i> being a model organism in the world of microalgae research, its presence at iGEM has been virtually non-existent. With a few exceptions like <a href="https://2014.igem.org/Team:Concordia" target="_blank">Concordia 2014</a> and <a href="https://2012.igem.org/Team:Valencia" target="_blank">Valencia 2012</a>, microalgae has made little of an appearance. While we hope our protein expression plasmid makes it easier for future teams to use <i>Chlamydomonas reinhardtii</i>, we went further by contributing to a dedicated non-model organisms guide.</p>
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<p>The partnership, facilitated by <a href="https://2015.igem.org/Team:Yale" target="_blank">Yale 2015</a>, includes the following five teams: <a href="https://2015.igem.org/Team:Concordia" target="_blank">Concordia 2015</a>, <a href="https://2015.igem.org/Team:Cornell" target="_blank">Cornell 2015</a>, <a href="https://2015.igem.org/Team:British_Columbia" target="_blank">University of British Columbia 2015</a>, <a href="https://2015.igem.org/Team:LaVerne-Leos" target="_blank">University of La Verne</a>, and <a href="https://2015.igem.org/Team:Utah_State" target="_blank">Utah State University 2015</a>.</p>
  
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<p><i>"Dr. George D. Yancopoulos, chief scientific officer of Regeneron, said the crisis had pointed up shortcomings in biodefense. “Nobody is really prepared,” he said. “Nobody in the world has rapid response capabilities.”</i>—New York Times, January 2015</p>
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    <p id="project_description__p__one">Northeastern is working to standardize protein production in microalgae. <i>Chlamydomonas reinhardtii</i>, the workhorse of algae research, is an attractive chassis for several reasons. Its primary carbon source is CO<sub>2</sub>, it rapidly divides, and it’s a capable of complex post-translational modifications.</p>
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<p>The guide itself appropriately stresses the need for both time and resources for non-<i>E. coli</i> species and emphasizes the utility of in-lab experience to help guide the project. We hope it is of use for future iGEM teams.</p>
  
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<p>Microalgae are relatively inexpensive to scale, yet have all the production capabilities of other Eukaryotic organisms (di-sulfide bonds and glycosylation). This capability could be exploited to treat human disease. For example, there was a shortage of an “antibody-cocktail” during the Ebola outbreak.</p>
 
  
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Latest revision as of 06:47, 18 September 2015

COLLABORATION

Handbook for non-model iGEM organisms

Despite Chlamydomonas reinhardtii being a model organism in the world of microalgae research, its presence at iGEM has been virtually non-existent. With a few exceptions like Concordia 2014 and Valencia 2012, microalgae has made little of an appearance. While we hope our protein expression plasmid makes it easier for future teams to use Chlamydomonas reinhardtii, we went further by contributing to a dedicated non-model organisms guide.

The partnership, facilitated by Yale 2015, includes the following five teams: Concordia 2015, Cornell 2015, University of British Columbia 2015, University of La Verne, and Utah State University 2015.

The guide itself appropriately stresses the need for both time and resources for non-E. coli species and emphasizes the utility of in-lab experience to help guide the project. We hope it is of use for future iGEM teams.