Difference between revisions of "Team:Pretoria UP"
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− | < | + | <img id="Banner" alt="Banner By Natascha Muller" src="/wiki/images/0/03/Banner_Pretoria_UP.png" style="width:30%; padding-top:7.5%;"/> |
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− | < | + | <!--<h4 id="description">SYNCHRONIZED, CONDITIONAL, GENETIC CHEMOTAXIS PROGRAMMING</h4>--> |
− | <h4 id="description">SYNCHRONIZED, CONDITIONAL, GENETIC CHEMOTAXIS PROGRAMMING</h4> | + | <h2 id="description"> Synchronized, Conditional, Genetic Chemotaxis Programming </h2> |
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− | <img id="animation" alt="Animation by Schae Ind" src="/wiki/images/1/15/Up_animation.gif"/> | + | <img id="animation" alt="Animation by Schae Ind" src="/wiki/images/1/15/Up_animation.gif" /> |
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− | The Pretoria UP iGEM team of 2015 have proposed a | + | The Pretoria UP iGEM team of 2015 have proposed a design for intelligent motile bacteria based on a combination of DNA modules that confer different functions. The synchronous behaviour of the bacteria will be achieved through a quorum sensing module allowing the population to behave as a swarm instead of independent units. A conditional response to an environmental signal is conferred through a post transcriptional control mechanism known as riboswitching, thus the bacterial swarm may recognise and respond to a chemical attractant. Since the system makes use of several modular components, an AND gate is required to process the various signals which in turn would trigger a genetic switch in the bacterial chemotaxis. The irreversible change is programmed by a DNA recombination switch which inverts the directionality of a promoter through the Cre-loxP pathway. We invite you to explore the various aspects of the project on this site. |
</p> | </p> | ||
Latest revision as of 22:00, 18 September 2015
Project Description
The Pretoria UP iGEM team of 2015 have proposed a design for intelligent motile bacteria based on a combination of DNA modules that confer different functions. The synchronous behaviour of the bacteria will be achieved through a quorum sensing module allowing the population to behave as a swarm instead of independent units. A conditional response to an environmental signal is conferred through a post transcriptional control mechanism known as riboswitching, thus the bacterial swarm may recognise and respond to a chemical attractant. Since the system makes use of several modular components, an AND gate is required to process the various signals which in turn would trigger a genetic switch in the bacterial chemotaxis. The irreversible change is programmed by a DNA recombination switch which inverts the directionality of a promoter through the Cre-loxP pathway. We invite you to explore the various aspects of the project on this site.