Difference between revisions of "Team:KU Leuven/Symposium"

 
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    <div class="summarytext1">
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          <div class="part">
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            <h2>
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                Event summary
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            </h2>
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            <p>
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                On September the 7th, 2015 we organized the <b>KU Leuven iGEM 2015 Symposium on Synthetic Biology, Cell Systems and Ethics in Biochemistry</b>. Hosted guests included 4 neighbouring iGEM teams, academic staff, students, sponsors, and iGEM supporters from 6 different European countries. During this full-day event, the participants had a chance to attend the lectures by home speakers as well as by invited international keynote speakers from both the academia and the industry. The iGEM teams presented their research, and probably the most awaited part - the debate on ethics in biochemistry with panel of well selected experts lead by an experienced professional moderator - took place in the afternoon. To fulfil all the needs, goodie-bags, drinks, lunch, and dinner were provided to our guests. The day finished with a sightseeing walk around Leuven centre. Participation was free of charge. We hosted almost a hundred guests and received a very positive feedback. <br/></p>
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                <br/>
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                <br/>
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                  <div class="quote">
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                    <h2>
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                      Evaluation form quotes
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                    </h2>
 +
                    <p>
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                    "Very professionally organized. Very well run. Great speakers - diverse agenda." <br/>
 +
                    "The lectures were super interesting!" <br/>
 +
                    "Great symposium, I loved it!!" <br/>
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                    "Amazing keynote speakers and a fantastic moderator. Everything was perfectly organized.” <br/>
 +
                    "Food was very good!" <br/>
 +
                    "It was the best symposium I have ever attended!!! Outstanding organization!!!" <br/>
 +
                    "Very good symposium. The keynote speakers were marvellous, the debate was interesting, with panel members who were very well selected!" <br/>
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                    <p>
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                  </div>
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                </div>
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<div class="whiterow"></div>
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            <p>
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                Home speaker <b>Vera van Noort</b> talked about lessons from systems biology of a
 +
                minimal organism for synthetic biology. In the EMBL, where she worked, they
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                wanted to completely describe one organism, namely <i>Mycoplasma
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                pneumoniae</i>. For complete understanding, three different levels were studied: <br/>
 +
                The metabolism, transcription (regulation) and protein complexes. The take-home
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                messages for synthetic biology in short: transcription regulation is more than
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                operons and transcription factors; enzymes can catalyse multiple reactions and
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                are organized in multi-subunit complexes; proteins can be part of multiple
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                complexes and can be regulated by post-translational modifications and small
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                peptides are essential. <br/><br/>
 +
                <b>Victor Dillard</b>, the first keynote speaker, is the
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                founder of Desktop Genetics. The company is building software for biologists,
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                with a focus on synthetic biology. The software helps to improve the efficiency
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                and to lower the costs. He explained that genome editing remains hard and became
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                a design and software challenge, and not purely biological challenge. This is
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                because genome editing needs to be accurate, precise, effective and rapid.<br/><br/>
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                <b>Sebastian Maerkl</b>, the second keynote speaker, discussed the topic cell-free
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                synthetic biology. He explained that microfluidics with cell-free lysate can be
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                used for rapid prototyping of biological systems. One of the advantages is that
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                it has defined and controllable reaction conditions. <i>In vitro</i> prototyping is
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                used to speed up research in synthetic biology. The pipeline of cell-free
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                synthetic biology: design a biological circuit, build the circuit, test parts
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                and circuits, characterize working circuits, clone and implement <i>in vivo</i>.<br/><br/>
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                The second home speaker, <b>Yves Peeters</b>, gave a talk about directed evolution of
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                polymerases using synthetic biology methods. The research of Yves Peeters is
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                part of the research domain Xenobiology, creating alternative life, one of the
 +
                approaches of synthetic biology. XNA, also called orthogonal DNA, is designed by
 +
                several labs using different strategies. Making organisms with XNA will be an
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                ultimate biosafety tool for synthetic biology. Before being able to have a
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                liveable organism that uses XNA, there is a need for polymerases recognizing the
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                specific XNA. To create the wanted polymerases, Yves uses directed evolution,
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                including mutagenesis, screening, amplification and iteration of the most active
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                enzymes.<br/>
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            </p>
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                iGEM teams at the symposium."><img class="example-image"
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                src="https://static.igem.org/mediawiki/2015/b/b6/KU_Leuven_symp_cut.JPG" alt="Photo of the participating speakers and
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                iGEM teams at the symposium. " width="49%" height="49%"></a>
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                data-lightbox="example-set"> </a> 
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                data-lightbox="example-set"> </a> 
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                <h4><div id=figure2></div> Photo of the
 +
                participating speakers and iGEM teams at the symposium. Click and  on image and use arrow buttons
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                to browse trough more pictures. </h4>
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              </div>
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            </div>
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          </div>
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        </div>
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 +
  <div class="part">
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        <h3 style="font-size:2.7em">PARTICIPATING iGEM TEAMS</h3><br>
 +
        <div>
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            <div class="linewrapper">
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                <div align="left" class="teamswrapper" id="left" name="KUL"
 +
                    style="cursor:pointer;">
 +
                    <a href="https://2015.igem.org/Team:KU_Leuven">
 +
                        <img height=100px src="https://static.igem.org/mediawiki/2015/7/76/KUL_SYM_logo.png"
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                            width=200px>
 +
                    </a>
 +
                </div>
 +
 
 +
                <div class="teamswrapper" id="middle" name="AMS" style="cursor:pointer;">
 +
                    <a href="https://2015.igem.org/Team:Amsterdam">
 +
                        <img height=120px
 +
                            src="https://static.igem.org/mediawiki/2015/8/81/KUL_Amsterdam_iGEM_logo_transparant.png"
 +
                            width=200px >
 +
                    </a>
 +
                </div>
 +
 
 +
                <div align="right" class="teamswrapper" id="right" name="PAR"
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                    style="cursor:pointer;">
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                    <a href="https://2015.igem.org/Team:Paris_Saclay">
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                        <img height=120px
 +
                            src="https://static.igem.org/mediawiki/2015/a/ab/KUL_logo_Paris_Saclay_logo_transparant.png
 +
"
 +
                            width=200px>
 +
                    </a>
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            </div>
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 +
                <div align="left" class="teamswrapper" id="left" name="EIN"
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                    style="cursor:pointer;">
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                    <a href="https://2015.igem.org/Team:TU_Eindhoven">
 +
                        <img height=120px src="https://static.igem.org/mediawiki/2015/0/06/Logo_website.png"
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                            width=200px>
 +
                    </a>
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                </div>
 +
 
 +
                <div class="teamswrapper" id="middle" name="BONN" style="cursor:pointer;">
 +
                    <a href="http://2015.igembonn.com">
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                        <img height=120px src="https://static.igem.org/mediawiki/2015/f/fb/KUL_Bonn.jpg"
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                            width=200px>
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                    </a>
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                </div>
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            </div>
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        </div>
 +
    </div>  
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     <div class="summarytext1">
 
     <div class="summarytext1">
 
         <div class="part">
 
         <div class="part">
            <h2 style="font-size:3.2em">iGEM Symposium Day on Synthetic Biology, Cell Systems and Ethics in Biochemistry</h2>
 
            <br>
 
  
 +
            <h3 style="font-size:2.7em">Speakers</h3><br>
 +
 +
            <p style="margin-bottom:20px">
 +
                <img ; align="left" height=225px
 +
                    src="https://static.igem.org/mediawiki/2015/f/f8/KU_Leuven_Speaker_SM.jpg"
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                    style="margin: 0px 20px 0px 0px;border:3px solid black" width="150px">
 +
                <u>
 +
                    <b>Sebastian Maerkl</b>, École Polytechnique Fédérale de Lausanne, The
 +
                    Laboratory of Biological Network Characterization (LBNC)</u>
 +
                <br>
 +
                Sebastian Maerkl's lab conducts research at the interface of engineering and
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                biology and is active in the areas of systems biology, synthetic biology and
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                molecular diagnostics. They are driven by the desire to learn how to rationally
 +
                design and engineer biological systems. Sebastian Maerkl’s research aims to
 +
                develop new microfluidic technologies and apply them to solve biological
 +
                problems. His rare expertise allows him to combine the design of new tools with
 +
                advanced research in biology. Sebastian Maerkl is internationally recognized for
 +
                his many outstanding contributions. Particularly in combining synthetic biology
 +
                and computational systems with microfluidics, he demonstrated that the
 +
                expression of genes in vivo can be provided based on the binding energy profiles
 +
                in vitro. His studies will focus on five areas: the bioengineering of
 +
                biosystems, the engineering of transcriptional regulatory networks, the
 +
                engineering of genes and genomes, the engineering of biological systems de novo
 +
                and the development of a new generation of diagnostic devices.
 +
            </p>
 +
        </div>
 +
    </div>
 +
    <br>
 +
    <br>
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    <br>
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    <br>
 +
    <div class="summarytext1">
 +
        <div class="part">
 +
            <p style="margin-bottom:20px">
 +
                <img ; align="right" height="210px"
 +
                    src="https://static.igem.org/mediawiki/2015/archive/7/7f/20150820114120%21KUL_SYM_VD.png"
 +
                    style="margin: 0px 0px 0px 20px;border:3px solid black" width="180px">
 +
                <u>
 +
                    <b>Victor Dillard</b>, Chief Operating Officer & Founder, Desktop Genetics</u>
 +
                <br>
 +
                Victor obtained his masters in chemical engineering with honours at Imperial
 +
                College London before completing a specialist biotechnology and business masters
 +
                with distinction at the University of Cambridge. Since graduating, Victor
 +
                founded Desktop Genetics with a vision to change modern biotech R&D and enable
 +
                rapid and accurate end-to-end genome engineering experiments through their
 +
                proprietary software platform. Within two years of founding Desktop Genetics,
 +
                Victor has raised over $600,000 of private equity and grant financing, and
 +
                delivered over $400,000 of revenue. Today, Victor heads the company's business
 +
                development and operations and is leading the product and technology expansion
 +
                into CRISPR and genome editing.
 +
            </p>
 +
        </div>
 +
    </div>
 +
    <div class="whitespace"></div>
 +
    <br>
 +
    <br>
 +
    <br>
 +
    <br>
 +
    <div class="summarytext1">
 +
        <div class="part">
 +
            <p>
 +
                <img ; align="left" height=200px
 +
                    src="https://static.igem.org/mediawiki/2015/b/b7/KUL_SYM_VVN.png"
 +
                    style="margin-right:20px" width="150px">
 +
                <u>
 +
                    <b>Vera van Noort</b>, Center for Microbial and Plant Genetics
 +
                </u><br>
 +
                The research group led by Vera van Noort is interested in understanding
 +
                biological systems as a whole. They try to achieve this through computational
 +
                analysis of large-scale data generated by the ever growing number of new
 +
                technologies that can systematically measure the behaviour of multiple cellular
 +
                components, such as biochemical activities, biophysical properties, subcellular
 +
                localization and interaction. They use and develop new methods to integrate,
 +
                visualize and query the large amounts of information available and in such a way
 +
                come to new biological discoveries. A particular focus of the group is
 +
                proteomics and post-translational modifications.
 +
            </p>
 +
        </div>
 +
    </div>
 +
    <div class="whitespace"></div>
 +
    <br>
 +
    <br>
 +
    <br>
 +
    <br>
 +
    <br>
 +
    <br>
 +
    <br>
 +
    <div class="summarytext1">
 +
        <div class="part">
 +
            <p>
 +
                <img align="right" height=200px
 +
                    src="https://static.igem.org/mediawiki/2015/e/e2/KUL_SYM_YP.png"
 +
                    style="margin-left:20px;border:3px solid black;z-index:100;" width="140px">
 +
                <u>
 +
                    <b>Yves Peeters</b>, Laboratory of Biochemistry, Molecular and Structural Biology</u>
 +
                <br>
 +
                After completing his master thesis at KU Leuven, Yves obtained an IWT fellowship
 +
                for his PhD work in the field of synthetic biology. His primary interest goes to
 +
                DNA polymerases and their modifications towards creation of artificial nucleic
 +
                acids.
 +
            </p>
 +
        </div>
 +
    </div>
 +
    <br>
 +
    <br>
 +
    <br>
 +
    <br>
 +
   
 +
<div class="summarytext1">
 +
        <div class="part">
 
             <h3 style="font-size:2.7em">Details</h3>
 
             <h3 style="font-size:2.7em">Details</h3>
 
             <br>
 
             <br>
Line 329: Line 638:
 
         </div>
 
         </div>
 
     </div>
 
     </div>
    <div class="summarytext1">
 
        <div class="part">
 
  
            <h3 style="font-size:2.7em">Speakers</h3><br>
 
 
            <p style="margin-bottom:20px">
 
                <img ; align="left" height=225px
 
                    src="https://static.igem.org/mediawiki/2015/f/f8/KU_Leuven_Speaker_SM.jpg"
 
                    style="margin: 0px 20px 0px 0px;border:3px solid black" width="150px">
 
                <u>
 
                    <b>Sebastian Maerkl</b>, École Polytechnique Fédérale de Lausanne, The
 
                    Laboratory of Biological Network Characterization (LBNC)</u>
 
                <br>
 
                Sebastian Maerkl's lab conducts research at the interface of engineering and
 
                biology and is active in the areas of systems biology, synthetic biology and
 
                molecular diagnostics. They are driven by the desire to learn how to rationally
 
                design and engineer biological systems. Sebastian Maerkl’s research aims to
 
                develop new microfluidic technologies and apply them to solve biological
 
                problems. His rare expertise allows him to combine the design of new tools with
 
                advanced research in biology. Sebastian Maerkl is internationally recognized for
 
                his many outstanding contributions. Particularly in combining synthetic biology
 
                and computational systems with microfluidics, he demonstrated that the
 
                expression of genes in vivo can be provided based on the binding energy profiles
 
                in vitro. His studies will focus on five areas: the bioengineering of
 
                biosystems, the engineering of transcriptional regulatory networks, the
 
                engineering of genes and genomes, the engineering of biological systems de novo
 
                and the development of a new generation of diagnostic devices.
 
            </p>
 
        </div>
 
    </div>
 
    <br>
 
    <br>
 
    <br>
 
    <br>
 
 
     <div class="summarytext1">
 
     <div class="summarytext1">
         <div class="part">
+
         <div class="part"
             <p style="margin-bottom:20px">
+
        <br>
                <img ; align="right" height="210px"
+
        <br>
                    src="https://static.igem.org/mediawiki/2015/archive/7/7f/20150820114120%21KUL_SYM_VD.png"
+
        <h2 style="font-size:2.7em">Drinks and food</h2>
                    style="margin: 0px 0px 0px 20px;border:3px solid black" width="180px">
+
        <p>
                <u>
+
             Beverages, lunch sandwiches and dinner-reception where be provided for all the
                    <b>Victor Dillard</b>, Chief Operating Officer & Founder, Desktop Genetics</u>
+
            participants free of charge.
                <br>
+
        </p>
                Victor obtained his masters in chemical engineering with honours at Imperial
+
        <br>
                College London before completing a specialist biotechnology and business masters
+
        <br>
                with distinction at the University of Cambridge. Since graduating, Victor
+
        <p>
                founded Desktop Genetics with a vision to change modern biotech R&D and enable
+
            <h2 style="font-size:2.7em">Map</h2><br>
                rapid and accurate end-to-end genome engineering experiments through their
+
            <img height=80%
                proprietary software platform. Within two years of founding Desktop Genetics,
+
                src="https://static.igem.org/mediawiki/2015/1/17/KUL_Campus_Arenberg.png" width=100%>
                Victor has raised over $600,000 of private equity and grant financing, and
+
        </p>
                delivered over $400,000 of revenue. Today, Victor heads the company's business
+
                development and operations and is leading the product and technology expansion
+
                into CRISPR and genome editing.
+
            </p>
+
        </div>
+
 
     </div>
 
     </div>
     <div class="whitespace"></div>
+
 
    <br>
+
     <br/>
    <br>
+
    <br/>
    <br>
+
</div>
    <br>
+
   
    <div class="summarytext1">
+
          <div class="subsections">
        <div class="part">
+
            <div class="subsectionwrapper">
            <p>
+
                <div class="subimgrow">
                <img ; align="left" height=200px
+
                    <div class="whitespace1"></div>
                     src="https://static.igem.org/mediawiki/2015/b/b7/KUL_SYM_VVN.png"
+
                    <div class="subimg">
                    style="margin-right:20px" width="150px">
+
                        <a href="https://2015.igem.org/Team:KU_Leuven/Outreach/Survey">
                 <u>
+
                            <img
                     <b>Vera van Noort</b>, Center for Microbial and Plant Genetics
+
                                src="https://static.igem.org/mediawiki/2015/3/36/KU_Leuven_Wiki_Button_-_Survey2.png"
                </u><br>
+
                                width="100%">
                The research group led by Vera van Noort is interested in understanding
+
                        </a>
                biological systems as a whole. They try to achieve this through computational
+
                    </div>
                analysis of large-scale data generated by the ever growing number of new
+
 
                technologies that can systematically measure the behaviour of multiple cellular
+
                    <div class="whitespace"></div>
                components, such as biochemical activities, biophysical properties, subcellular
+
 
                localization and interaction. They use and develop new methods to integrate,
+
                    <div class="subimg">
                visualize and query the large amounts of information available and in such a way
+
                        <a href="https://2015.igem.org/Team:KU_Leuven/Practices/Public">
                 come to new biological discoveries. A particular focus of the group is
+
                            <img
                 proteomics and post-translational modifications.
+
                                src="https://static.igem.org/mediawiki/2015/8/84/KU_Leuven_Wiki_Button_-_Outreach2.png"
            </p>
+
                                width="100%">
        </div>
+
                        </a>
    </div>
+
                     </div>
    <div class="whitespace"></div>
+
 
    <br>
+
                    <div class="whitespace"></div>
    <br>
+
 
    <br>
+
                    <div class="subimg">
    <br>
+
                        <a href="https://2015.igem.org/Team:KU_Leuven/Practices/Ethics">
    <br>
+
                            <img
    <br>
+
                                src="https://static.igem.org/mediawiki/2015/7/70/KU_Leuven_Wiki_Button_-_Ethics2.png"
    <br>
+
                                width="100%">
    <div class="summarytext1">
+
                        </a>
        <div class="part">
+
                    </div>
             <p>
+
                    <div class="whitespace1"></div>
                 <img align="right" height=200px
+
                 </div>
                     src="https://static.igem.org/mediawiki/2015/e/e2/KUL_SYM_YP.png"
+
 
                     style="margin-left:20px;border:3px solid black;z-index:100;" width="140px">
+
                <div class="subtextrow">
                <u>
+
                     <div class="whitespace1"></div>
                     <b>Yves Peeters</b>, Laboratory of Biochemistry, Molecular and Structural Biology</u>
+
                    <div class="subtext">
                 <br>
+
                        <a href="https://2015.igem.org/Team:KU_Leuven/Outreach/Survey">
                After completing his master thesis at KU Leuven, Yves obtained an IWT fellowship
+
                            <h2>Survey</h2>
                 for his PhD work in the field of synthetic biology. His primary interest goes to
+
                            <p>We conducted a survey to shed light on the perception of synthetic biology in
                DNA polymerases and their modifications towards creation of artificial nucleic
+
                                Belgium.
                acids.
+
                            </p>
            </p>
+
                        </a>
        </div>
+
                    </div>
    </div>
+
 
    <br>
+
                    <div class="whitespace"></div>
    <br>
+
 
    <br>
+
                    <div class="subtext">
    <br>
+
                        <a href="  https://2015.igem.org/Team:KU_Leuven/Practices/Public">
    <br>
+
                            <h2>Public Engagement</h2>
    <br>
+
                            <p>How we engaged generally and intra university-wise.
    <br>
+
                            </p>
    <br>
+
                        </a>
    <div class="part">
+
                    </div>
        <h3 style="font-size:2.7em">PARTICIPATING iGEM TEAMS</h3><br>
+
 
        <div>
+
                    <div class="whitespace"></div>
            <div class="linewrapper">
+
 
                 <div align="left" class="teamswrapper" id="left" name="KUL"
+
                    <div class="subtext">
                    style="cursor:pointer;">
+
                        <a href="https://2015.igem.org/Team:KU_Leuven/Practices/Ethics">
                     <a href="https://2015.igem.org/Team:KU_Leuven">
+
                            <h2>Ethics</h2>
                         <img height=100px src="https://static.igem.org/mediawiki/2015/7/76/KUL_SYM_logo.png"
+
                            <p>
                             width=200px>
+
                                What we learned from a panel of experts we invited to discuss ethical and legal
 +
                                questions.
 +
                            </p>
 +
                        </a>
 +
                    </div>
 +
                    <div class="whitespace1"></div>
 +
                 </div>
 +
 
 +
                 <div class="subimgreadmore">
 +
                    <div class="whitespace1"></div>
 +
                    <div class="subimgrm">
 +
                        <a href="https://2015.igem.org/Team:KU_Leuven/Outreach/Survey">
 +
                            <div id="more">
 +
                                <img alt="Read more" height="40%"
 +
                                    src="https://static.igem.org/mediawiki/2015/7/73/KUL_Wiki_Button_-_Read_more.png"
 +
                                    width="85%">
 +
                            </div>
 +
                        </a>
 +
                    </div>
 +
 
 +
                    <div class="whitespace"></div>
 +
 
 +
                    <div class="subimgrm">
 +
                        <a href="https://2015.igem.org/Team:KU_Leuven/Practices/Public">
 +
                            <div id="more">
 +
                                <img alt="Read more" height="40%"
 +
                                    src="https://static.igem.org/mediawiki/2015/7/73/KUL_Wiki_Button_-_Read_more.png"
 +
                                    width="85%">
 +
                            </div>
 +
                        </a>
 +
                    </div>
 +
 
 +
                    <div class="whitespace"></div>
 +
 
 +
                    <div class="subimgrm">
 +
                        <a href="https://2015.igem.org/Team:KU_Leuven/Practices/Ethics">
 +
                            <div id="more">
 +
                                <img alt="Read more" height="40%"
 +
                                    src="https://static.igem.org/mediawiki/2015/7/73/KUL_Wiki_Button_-_Read_more.png"
 +
                                    width="85%">
 +
                            </div>
 +
                        </a>
 +
                    </div>
 +
                    <div class="whitespace1"></div>
 +
                </div>
 +
            </div>
 +
            <div class="whiterow"></div>
 +
             <div class="subsectionwrapper">
 +
                 <div class="subimgrow">
 +
                    <div class="whitespace1"></div>
 +
                    <div class="subimg">
 +
                        <a href="https://2015.igem.org/Team:KU_Leuven/Practices/Education">
 +
                            <img
 +
                                src="https://static.igem.org/mediawiki/2015/7/78/KU_Leuven_Wiki_Button_-_Education2.png"
 +
                                width="100%">
 +
                        </a>
 +
                     </div>
 +
 
 +
                    <div class="whitespace"></div>
 +
 
 +
                    <div class="subimg">
 +
                        <a href="https://2015.igem.org/Team:KU_Leuven/Collaborations">
 +
                            <img
 +
                                src="https://static.igem.org/mediawiki/2015/e/e0/KU_Leuven_Wiki_Button_-_Collaboration2.png"
 +
                                width="100%">
 +
                        </a>
 +
                     </div>
 +
 
 +
                    <div class="whitespace"></div>
 +
 
 +
                  <div class="subimg">
 +
                        <a href="https://2015.igem.org/Team:KU_Leuven/Practices">
 +
                            <img src="https://static.igem.org/mediawiki/2015/c/cb/KUL_Wiki_Button_-_Back.png"
 +
                                width="100%">
 +
                        </a>
 +
                     </div>
 +
 
 +
                    <div class="whitespace1"></div>
 +
                 </div>
 +
 
 +
                 <div class="subtextrow">
 +
                    <div class="whitespace1"></div>
 +
                    <div class="subtext">
 +
                        <a href="https://2015.igem.org/Team:KU_Leuven/Practices/Education">
 +
                            <h2>Education</h2>
 +
                            <p>
 +
                                We went teaching and devised an educational card game, which is fun to play.
 +
                            </p>
 +
                        </a>
 +
                    </div>
 +
 
 +
                    <div class="whitespace"></div>
 +
 
 +
                    <div class="subtext">
 +
                        <a href="https://2015.igem.org/Team:KU_Leuven/Collaborations">
 +
                            <h2>Collaborations</h2>
 +
                            <p>
 +
                                We worked together with other teams to improve both projects.
 +
                            </p>
 +
                        </a>
 +
                    </div>
 +
 
 +
                    <div class="whitespace"></div>
 +
 
 +
                    <div class="subtext">
 +
 
 +
                        <a href="https://2015.igem.org/Team:KU_Leuven/Practices">
 +
                            <h2>Back</h2>
 +
                            <p>
 +
                                Go back to the Outreach page.
 +
                            </p>
 +
                        </a>
 +
                    </div>
 +
 
 +
                    <div class="whitespace1"></div>
 +
                 </div>
 +
 
 +
                <div class="subimgreadmore">
 +
                    <div class="whitespace1"></div>
 +
                    <div class="subimgrm">
 +
                        <a href="https://2015.igem.org/Team:KU_Leuven/Practices/Education">
 +
                            <div id="more">
 +
                                <img alt="Read more" height="40%"
 +
                                    src="https://static.igem.org/mediawiki/2015/7/73/KUL_Wiki_Button_-_Read_more.png"
 +
                                    width="85%">
 +
                            </div>
 +
                        </a>
 +
                     </div>
 +
 
 +
                    <div class="whitespace"></div>
 +
 
 +
                    <div class="subimgrm">
 +
                        <a href="https://2015.igem.org/Team:KU_Leuven/Collaborations">
 +
                            <div id="more">
 +
                                <img alt="Read more" height="40%"
 +
                                    src="https://static.igem.org/mediawiki/2015/7/73/KUL_Wiki_Button_-_Read_more.png"
 +
                                    width="85%">
 +
                            </div>
 +
                         </a>
 +
                    </div>
 +
 
 +
                    <div class="whitespace"></div>
 +
 
 +
                    <div class="subimgrm">
 +
                        <a href="https://2015.igem.org/Team:KU_Leuven/Practices">
 +
                            <div id="back">
 +
                                <img alt="Read more" height="40%"
 +
                                    src="https://static.igem.org/mediawiki/2015/7/73/KUL_Wiki_Button_-_Read_more.png"
 +
                                    width="85%">
 +
                             </div>
 +
                        </a>
 +
                    </div>
 +
 
 +
 
 +
                    <div class="whitespace1"></div>
 +
                </div>
 +
 
 +
                <!--          Mobile starts here!!!        -->
 +
                <div class="subimgrowm">
 +
                    <a href="https://2015.igem.org/Team:KU_Leuven/Outreach/Survey">
 +
                        <div class="subimgm">
 +
                            <b>Survey</b>
 +
                            <img
 +
                                src="https://static.igem.org/mediawiki/2015/3/36/KU_Leuven_Wiki_Button_-_Survey2.png"
 +
                                width="100%">
 +
                        </div>
 +
 
 +
                        <div class="whitespace"></div>
 +
 
 +
                        <div class="subtextm">
 +
                            <p>
 +
                                We did a survey to shed light on the perception of synthetic biology in belgium.
 +
                            </p>
 +
                        </div>
 
                     </a>
 
                     </a>
 +
                </div>
  
 +
                <div class="subimgrowm">
 +
                    <div class="whiterow"></div>
 
                 </div>
 
                 </div>
  
                 <div class="teamswrapper" id="middle" name="AMS" style="cursor:pointer;">
+
                 <div class="subimgrowm">
                     <a href="https://2015.igem.org/Team:Amsterdam">
+
                     <a href="https://2015.igem.org/Team:KU_Leuven/Practices/Public">
                         <img height=120px
+
                         <div class="subimgm">
                             src="https://static.igem.org/mediawiki/2015/8/81/KUL_Amsterdam_iGEM_logo_transparant.png"
+
                             <b>Public Engagement</b>
                            width=200px >
+
                            <img
 +
                                src="https://static.igem.org/mediawiki/2015/8/84/KU_Leuven_Wiki_Button_-_Outreach2.png"
 +
                                width="100%">
 +
                        </div>
 +
 
 +
                        <div class="whitespace"></div>
 +
 
 +
                        <div class="subtextm">
 +
                            <p>
 +
                                How we engaged generally and intra university-wise.
 +
                            </p>
 +
                        </div>
 
                     </a>
 
                     </a>
 +
                </div>
  
 +
                <div class="subimgrowm">
 +
                    <div class="whiterow"></div>
 
                 </div>
 
                 </div>
  
                 <div align="right" class="teamswrapper" id="right" name="PAR"
+
                 <div class="subimgrowm">
                    style="cursor:pointer;">
+
                     <a href="https://2015.igem.org/Team:KU_Leuven/Practices/Ethics">
                     <a href="https://2015.igem.org/Team:Paris_Saclay">
+
                         <div class="subimgm">
                         <img height=120px
+
                             <b>Ethics</b>
                             src="https://static.igem.org/mediawiki/2015/a/ab/KUL_logo_Paris_Saclay_logo_transparant.png
+
                            <img
"
+
                                src="https://static.igem.org/mediawiki/2015/7/70/KU_Leuven_Wiki_Button_-_Ethics2.png"
                            width=200px>
+
                                width="100%">
 +
                        </div>
 +
 
 +
                        <div class="whitespace"></div>
 +
 
 +
                        <div class="subtextm">
 +
                            <p>
 +
                                We invited a panel of experts to discuss ethical questions with us.
 +
                            </p>
 +
                        </div>
 
                     </a>
 
                     </a>
 +
                </div>
  
 +
                <div class="subimgrowm">
 +
                    <div class="whiterow"></div>
 
                 </div>
 
                 </div>
            </div>
 
  
            <div class="linewrapper">
+
                 <div class="subimgrowm">
                 <div align="left" class="teamswrapper" id="left" name="EIN"
+
                     <a href="https://2015.igem.org/Team:KU_Leuven/Practices/Education">
                    style="cursor:pointer;">
+
                         <div class="subimgm">
                     <a href="https://2015.igem.org/Team:TU_Eindhoven">
+
                            <b>Education</b>
                         <img height=120px src="https://static.igem.org/mediawiki/2015/0/06/Logo_website.png"
+
                            <img
                            width=200px>
+
                                src="https://static.igem.org/mediawiki/2015/7/78/KU_Leuven_Wiki_Button_-_Education2.png"
 +
                                width="100%">
 +
                        </div>
 +
 
 +
                        <div class="whitespace"></div>
 +
 
 +
                        <div class="subtextm">
 +
                            <p>
 +
                                We went teaching and devised an educational card game, which is fun to play.
 +
                            </p>
 +
                        </div>
 
                     </a>
 
                     </a>
 +
                </div>
  
 +
                <div class="subimgrowm">
 +
                    <div class="whiterow"></div>
 
                 </div>
 
                 </div>
  
                 <div class="teamswrapper" id="middle" name="BONN" style="cursor:pointer;">
+
                 <div class="subimgrowm">
                     <a href="http://2015.igembonn.com">
+
                     <a href="https://2015.igem.org/Team:KU_Leuven/Collaborations">
                         <img height=120px src="https://static.igem.org/mediawiki/2015/f/fb/KUL_Bonn.jpg"
+
                         <div class="subimgm">
                            width=200px>
+
                            <b>Collaborations</b>
 +
                            <img
 +
                                src="https://static.igem.org/mediawiki/2015/e/e0/KU_Leuven_Wiki_Button_-_Collaboration2.png"
 +
                                width="100%">
 +
                        </div>
 +
                        <div class="whitespace"></div>
 +
 
 +
                        <div class="subtextm">
 +
                            <p>
 +
                                We worked together with other teams to improve both our projects.
 +
                            </p>
 +
                        </div>
 
                     </a>
 
                     </a>
 +
                </div>
  
 +
                <div class="subimgrowm">
 +
                    <div class="whiterow"></div>
 
                 </div>
 
                 </div>
            </div>
 
        </div>
 
  
        <br>
+
               
            <h2>
+
                 <div class="subimgrowm">
                 Event summary
+
                    <a href="https://2015.igem.org/Team:KU_Leuven/Practices">
            </h2>
+
                        <div class="subimgm">
            <p>
+
                            <b>Back</b>
                For the symposium, we invited and welcomed academic staff, students, sponsors
+
                            <img src="https://static.igem.org/mediawiki/2015/c/cb/KUL_Wiki_Button_-_Back.png"
                and iGEM supporters. About eighty people were present.<br/>
+
                                width="100%">
                Here you can find some quotes found on the evaluation forms of our symposium:
+
                        </div>
                <div class="center">
+
                        <div class="whitespace"></div>
                  <div class="quote">
+
 
                    "Very professionally organized. Very well run. Great speakers - diverse agenda." <br/>
+
                        <div class="subtextm">
                    "The lectures were super interesting!" <br/>
+
                            <p>
                    "Great symposium, I loved it!!" <br/>
+
                                Go back to the Outreach page.
                    "Amazing keynote speakers and a fantastic moderator. Everything was perfectly organized.” <br/>
+
                            </p>
                    "Food was very good!" <br/>
+
                        </div>
                    "It was the best symposium I have ever attended!!! Outstanding organization!!!" <br/>
+
                    </a>
                    "Very good symposium. The keynote speakers were marvellous, the debate was interesting, with panel members who were very well selected!" <br/>
+
                  </div>
+
 
                 </div>
 
                 </div>
                Home speaker Vera van Noort talked about the lessons from systems biology of a
+
 
                minimal organism for synthetic biology. In the EMBL where she worked, they
+
             </div>
                wanted to completely describe one organism. They worked on Mycoplasma
+
         </div>
                pneumoniae. To understand it completely, they studied three different levels:
+
                the metabolism, transcription (regulation) and protein complexes. The take-home
+
                lessons for synthetic biology in short: transcription regulation is more than
+
                operons and transcription factors, enzymes can catalyse multiple reactions and
+
                are organized in multi-subunit complexes, proteins can be part of multiple
+
                complexes and can be regulated by post-translational modifications and small
+
                peptides are essential. Victor Dillard, the first keynote speaker, is the
+
                founder of Desktop Genetics. The company is building software for biologists,
+
                with a focus on synthetic biology. The software helps to improve the efficiency
+
                and to lower the costs. He explained that genome editing remains hard and became
+
                a design and software challenge, and not purely biological challenge. This is
+
                because genome editing needs to be accurate, precise, effective and rapid.
+
                Sebastian Maerkl, the second keynote speaker, discussed the topic cell-free
+
                synthetic biology. He explained that microfluidics with cell-free lysate can be
+
                used for rapid prototyping of biological systems. One of the advantages is that
+
                it has defined and controllable reaction conditions. In vitro prototyping is
+
                used to speed up research in synthetic biology. The pipeline of cell-free
+
                synthetic biology: design a biological circuit, build the circuit, test parts
+
                and circuits, characterize working circuits, clone and implement in vivo. The
+
                second home speaker, Yves Peeters, gave a talk about directed evolution of
+
                polymerases using synthetic biology methods. The research of Yves Peeters is
+
                part of the research domain Xenobiology, creating alternative life, one of the
+
                approaches of synthetic biology. XNA, also called orthogonal DNA, is designed by
+
                several labs using different strategies. Making organisms with XNA will be an
+
                ultimate biosafety tool for synthetic biology. Before being able to have a
+
                liveable organism that uses XNA, there is a need for polymerases recognizing the
+
                specific XNA. To create the wanted polymerases, Yves uses directed evolution,
+
                including mutagenesis, screening, amplification and iteration of the most active
+
                enzymes.
+
             </p>
+
        <br>
+
        <br>
+
        <h2 style="font-size:2.7em">Drinks and food</h2>
+
        <p>
+
            Beverages, lunch sandwiches and dinner-reception where be provided for all the
+
            participants free of charge.
+
        </p>
+
        <br>
+
        <br>
+
        <p>
+
            <h2 style="font-size:2.7em">Map</h2><br>
+
            <img height=80%
+
                src="https://static.igem.org/mediawiki/2015/1/17/KUL_Campus_Arenberg.png" width=100%>
+
         </p>
+
 
     </div>
 
     </div>
  
    <br>
 
    <br>
 
    <br>
 
  
    <div id="summarywrapper">
+
  <div id="summarywrapper">
 
         <div class="summary">
 
         <div class="summary">
 
             <h3>
 
             <h3>
Line 576: Line 1,024:
 
             <p style="font-size:1.3em; text-align: center">
 
             <p style="font-size:1.3em; text-align: center">
 
                 Address: Celestijnenlaan 200G room 00.08 - 3001 Heverlee<br>
 
                 Address: Celestijnenlaan 200G room 00.08 - 3001 Heverlee<br>
                 Telephone : +32(0)16 32 73 19<br>
+
                 Telephone: +32(0)16 32 73 19<br>
                 Mail: igem@chem.kuleuven.be<br>
+
                 Email: igem@chem.kuleuven.be<br>
 
             </p>
 
             </p>
 
         </div>
 
         </div>
 
     </div>
 
     </div>
 +
 +
<div class="whiterow"></div>
  
 
     <div id="footer">
 
     <div id="footer">
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                     width="95%"></a>
 
                     width="95%"></a>
 
             </div>
 
             </div>
 +
<div id="saillart">
 +
      <a href="http://www.glasatelier-saillart.be/English/english.html"><img src="https://static.igem.org/mediawiki/2015/c/ce/KU_Leuven_Sponsor_Saillard.png" alt="Glasatelier Saillart" width="95%"></a>
 +
  </div>
 
             <div id="kuleuven">
 
             <div id="kuleuven">
 
                 <a href="http://www.kuleuven.be/english"><img alt="bioSCENTer"
 
                 <a href="http://www.kuleuven.be/english"><img alt="bioSCENTer"
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             </div>
 
             </div>
 
             <div id="kolo">
 
             <div id="kolo">
                 <a href=""><img alt="Ko-Lo Instruments"
+
                 <a><img alt="Ko-Lo Instruments"
 
                     src="https://static.igem.org/mediawiki/2015/1/15/KUL_Ko-Lo_Instruments_logo_transparant.png"
 
                     src="https://static.igem.org/mediawiki/2015/1/15/KUL_Ko-Lo_Instruments_logo_transparant.png"
                    width="95%"></a>
 
            </div>
 
            <div id="regensys">
 
                <a href="http://regenesys.eu/"><img alt="Regenesys"
 
                    src="https://static.igem.org/mediawiki/2015/e/eb/KU_Leuven_Logo_Regenesys_Transparant.png"
 
 
                     width="95%"></a>
 
                     width="95%"></a>
 
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Latest revision as of 10:04, 20 October 2015

Symposium

Event summary

On September the 7th, 2015 we organized the KU Leuven iGEM 2015 Symposium on Synthetic Biology, Cell Systems and Ethics in Biochemistry. Hosted guests included 4 neighbouring iGEM teams, academic staff, students, sponsors, and iGEM supporters from 6 different European countries. During this full-day event, the participants had a chance to attend the lectures by home speakers as well as by invited international keynote speakers from both the academia and the industry. The iGEM teams presented their research, and probably the most awaited part - the debate on ethics in biochemistry with panel of well selected experts lead by an experienced professional moderator - took place in the afternoon. To fulfil all the needs, goodie-bags, drinks, lunch, and dinner were provided to our guests. The day finished with a sightseeing walk around Leuven centre. Participation was free of charge. We hosted almost a hundred guests and received a very positive feedback.



Evaluation form quotes

"Very professionally organized. Very well run. Great speakers - diverse agenda."
"The lectures were super interesting!"
"Great symposium, I loved it!!"
"Amazing keynote speakers and a fantastic moderator. Everything was perfectly organized.”
"Food was very good!"
"It was the best symposium I have ever attended!!! Outstanding organization!!!"
"Very good symposium. The keynote speakers were marvellous, the debate was interesting, with panel members who were very well selected!"

Home speaker Vera van Noort talked about lessons from systems biology of a minimal organism for synthetic biology. In the EMBL, where she worked, they wanted to completely describe one organism, namely Mycoplasma pneumoniae. For complete understanding, three different levels were studied:
The metabolism, transcription (regulation) and protein complexes. The take-home messages for synthetic biology in short: transcription regulation is more than operons and transcription factors; enzymes can catalyse multiple reactions and are organized in multi-subunit complexes; proteins can be part of multiple complexes and can be regulated by post-translational modifications and small peptides are essential.

Victor Dillard, the first keynote speaker, is the founder of Desktop Genetics. The company is building software for biologists, with a focus on synthetic biology. The software helps to improve the efficiency and to lower the costs. He explained that genome editing remains hard and became a design and software challenge, and not purely biological challenge. This is because genome editing needs to be accurate, precise, effective and rapid.

Sebastian Maerkl, the second keynote speaker, discussed the topic cell-free synthetic biology. He explained that microfluidics with cell-free lysate can be used for rapid prototyping of biological systems. One of the advantages is that it has defined and controllable reaction conditions. In vitro prototyping is used to speed up research in synthetic biology. The pipeline of cell-free synthetic biology: design a biological circuit, build the circuit, test parts and circuits, characterize working circuits, clone and implement in vivo.

The second home speaker, Yves Peeters, gave a talk about directed evolution of polymerases using synthetic biology methods. The research of Yves Peeters is part of the research domain Xenobiology, creating alternative life, one of the approaches of synthetic biology. XNA, also called orthogonal DNA, is designed by several labs using different strategies. Making organisms with XNA will be an ultimate biosafety tool for synthetic biology. Before being able to have a liveable organism that uses XNA, there is a need for polymerases recognizing the specific XNA. To create the wanted polymerases, Yves uses directed evolution, including mutagenesis, screening, amplification and iteration of the most active enzymes.



Photo of the participating speakers and 
                iGEM teams at the symposium.

Photo of the participating speakers and iGEM teams at the symposium. Click and on image and use arrow buttons to browse trough more pictures.

PARTICIPATING iGEM TEAMS


Speakers


Sebastian Maerkl, École Polytechnique Fédérale de Lausanne, The Laboratory of Biological Network Characterization (LBNC)
Sebastian Maerkl's lab conducts research at the interface of engineering and biology and is active in the areas of systems biology, synthetic biology and molecular diagnostics. They are driven by the desire to learn how to rationally design and engineer biological systems. Sebastian Maerkl’s research aims to develop new microfluidic technologies and apply them to solve biological problems. His rare expertise allows him to combine the design of new tools with advanced research in biology. Sebastian Maerkl is internationally recognized for his many outstanding contributions. Particularly in combining synthetic biology and computational systems with microfluidics, he demonstrated that the expression of genes in vivo can be provided based on the binding energy profiles in vitro. His studies will focus on five areas: the bioengineering of biosystems, the engineering of transcriptional regulatory networks, the engineering of genes and genomes, the engineering of biological systems de novo and the development of a new generation of diagnostic devices.





Victor Dillard, Chief Operating Officer & Founder, Desktop Genetics
Victor obtained his masters in chemical engineering with honours at Imperial College London before completing a specialist biotechnology and business masters with distinction at the University of Cambridge. Since graduating, Victor founded Desktop Genetics with a vision to change modern biotech R&D and enable rapid and accurate end-to-end genome engineering experiments through their proprietary software platform. Within two years of founding Desktop Genetics, Victor has raised over $600,000 of private equity and grant financing, and delivered over $400,000 of revenue. Today, Victor heads the company's business development and operations and is leading the product and technology expansion into CRISPR and genome editing.





Vera van Noort, Center for Microbial and Plant Genetics
The research group led by Vera van Noort is interested in understanding biological systems as a whole. They try to achieve this through computational analysis of large-scale data generated by the ever growing number of new technologies that can systematically measure the behaviour of multiple cellular components, such as biochemical activities, biophysical properties, subcellular localization and interaction. They use and develop new methods to integrate, visualize and query the large amounts of information available and in such a way come to new biological discoveries. A particular focus of the group is proteomics and post-translational modifications.








Yves Peeters, Laboratory of Biochemistry, Molecular and Structural Biology
After completing his master thesis at KU Leuven, Yves obtained an IWT fellowship for his PhD work in the field of synthetic biology. His primary interest goes to DNA polymerases and their modifications towards creation of artificial nucleic acids.





Details


DATE:
07.09.2015 10:00 – 19:00
VENUE:
KU Leuven Campus Arenberg, Celestijnenlaan 200A (Computer Science) aula 00.225, Heverlee, Belgium



PROGRAM


KU Leuven iGEM 2015 Symposium
on Synthetic Biology, Cell Systems and Ethics in Biochemistry
Leuven 07.09.2015
9:00-10:00 Registration and welcome tea/coffee
Morning Block 10:00-10:10 Welcome words by Prof. Johan Robben
10:10-10:35 Home speaker: Vera van Noort
Center for Microbial and Plant Genetics
"Lessons from systems biology of a minimal organism for synthetic biology"
10:35-11:35 Keynote speaker: Victor Dillard
Chief Operating Officer & Founder, Desktop Genetics
"Through synthetic biology to entrepreneurship"
Presentation by the iGEM Teams
11:40-11:50 iGEM Paris-Saclay: "SafetE.coli"
11:55-12:05 iGEM TU Eindhoven: "Click Coli"
12:05-13:05 Lunch Break, networking
Early Afternoon Block 13:05-14:05 Keynote speaker: Sebastian Maerkl
École Polytechnique Fédérale de Lausanne, LBNC
"Cell-Free synthetic biology"
14:05-14:30 Home speaker: Yves Peeters
Laboratory of Biochemistry: Molecular and Structural Biology
"Directed evolution of polymerases using synthetic biology methods"
Presentation by the iGEM Teams
14:35-14:45 iGEM Amsterdam: "[Photo]Synthetic Romance"
14:50-15:00 iGEM TU Darmstadt: "Building with light/Labsurfing"
15:05-15:20 iGEM KU Leuven: "Spot E.Shape"
15:25-15:50 Tea/Coffee break
Evening block 15:50-16:00 Introduction of the debate experts: Prof. Bart De Moor (KU Leuven), Prof. Johan Robben (KU Leuven), Dr. Stijn Bruers (UGent), Prof. Vera van Noort (KU Leuven), Victor Dillard (Desktop Genetics).
Moderator: Prof. Piet Van der Meer (Ugent/VUB)
16:00-17:00 A debate on the ethics in synthetic biology and biochemistry
17:00-17:10 Closing words
17:10-19:00 Wok and Talk Chinese dinner reception
19:30 Leuven Kermis – Visit to Leuven Centrum for interested people




Drinks and food

Beverages, lunch sandwiches and dinner-reception where be provided for all the participants free of charge.



Map




Contact

Address: Celestijnenlaan 200G room 00.08 - 3001 Heverlee
Telephone: +32(0)16 32 73 19
Email: igem@chem.kuleuven.be