Difference between revisions of "Team:Freiburg/Home"
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<style> | <style> | ||
+ | .content_box{ | ||
+ | padding-top:500px; | ||
+ | |||
+ | } | ||
.homepage_headline{ | .homepage_headline{ | ||
text-align: center; | text-align: center; | ||
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#what_box, #how_box, #why_box{ | #what_box, #how_box, #why_box{ | ||
+ | padding-top:200px; | ||
position: relative; | position: relative; | ||
width: auto; | width: auto; | ||
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#what_box{ | #what_box{ | ||
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} | } | ||
#what_left{ | #what_left{ | ||
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#what_box{} | #what_box{} | ||
#what_text{ | #what_text{ | ||
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} | } | ||
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#how_box{ | #how_box{ | ||
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} | } | ||
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} | } | ||
#how_right{ | #how_right{ | ||
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} | } | ||
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#why_box{ | #why_box{ | ||
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} | } | ||
#why_image img{ | #why_image img{ | ||
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<div id="what_right" class="floatbox right"> | <div id="what_right" class="floatbox right"> | ||
<div id="what_diachip_logo"> | <div id="what_diachip_logo"> | ||
− | <img src="https://static.igem.org/mediawiki/2015/9/91/Freiburg_homepage_Dia_chip.png"> | + | <img src="https://static.igem.org/mediawiki/2015/9/91/Freiburg_homepage_Dia_chip.png"></img> |
</div> | </div> | ||
</div> | </div> | ||
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<div id="how_left" class="floatbox left"> | <div id="how_left" class="floatbox left"> | ||
<div id="how_image"> | <div id="how_image"> | ||
− | <img src="https://static.igem.org/mediawiki/2015/0/0f/Freiburg_homepage_chip_blood.png"> | + | <img src="https://static.igem.org/mediawiki/2015/0/0f/Freiburg_homepage_chip_blood.png"></img> |
</div> | </div> | ||
</div> | </div> | ||
− | <div id="how_right" class="floatbox right> | + | <div id="how_right" class="floatbox right"> |
<div class="homepage_headline">How are we doing it?</div> | <div class="homepage_headline">How are we doing it?</div> | ||
<div id="how_text" class="homepage_text"> | <div id="how_text" class="homepage_text"> | ||
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− | <div id="why_box"> | + | <div id="why_box" class="floatbox"> |
− | <div id="why_left"> | + | <div id="why_left" class="floatbox left"> |
<div class="homepage_headline">Why are we doing it?</div> | <div class="homepage_headline">Why are we doing it?</div> | ||
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− | <div id="why_right"> | + | <div id="why_right" class="floatbox right"> |
<div id="why_image"> | <div id="why_image"> | ||
− | <img src="https://static.igem.org/mediawiki/2015/b/b6/Freiburg_homepage_chip_denature.png"> | + | <img src="https://static.igem.org/mediawiki/2015/b/b6/Freiburg_homepage_chip_denature.png"></img> |
</div> | </div> | ||
</div> | </div> |
Revision as of 21:13, 3 September 2015
![](https://static.igem.org/mediawiki/2015/8/85/Freiburg_wiki_background_2_parted_left.png)
![](https://static.igem.org/mediawiki/2015/f/f4/Freiburg_wiki_background_2_parted_right.png)
![](https://static.igem.org/mediawiki/2015/9/91/Freiburg_homepage_Dia_chip.png)
![](https://static.igem.org/mediawiki/2015/0/0f/Freiburg_homepage_chip_blood.png)
![](https://static.igem.org/mediawiki/2015/b/b6/Freiburg_homepage_chip_denature.png)
Abstract
In modern medicine, fast detection and differentiation of diseases is a crucial and fundamental task. Typical ELISA-based assays are time-consuming and expensive. We propose an advanced procedure for the simultaneous detection of various diseases in a fast and inexpensive manner, the DiaCHIP. Our approach is based on the interaction of antibodies with their respective antigens. Different antigens are immobilized on a protein array generated by cell-free protein expression, using the corresponding DNA array as a template. Placed in a microfluidic chamber, the protein array is incubated with a patient’s blood sample. The interaction between an antibody in the sample and the corresponding immobilized antigen results in a local change of the optical thickness of the surface. This change can be detected using a label-free and real-time measurement technology called iRIf (imaging Reflectometric Interference)which is based on a laser detecting the interference of reflecting light from our chip. Offering simultaneous screening for several diseases, our DiaCHIP has strong potential to improve future diagnostics.