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| <li><a id="home" href="https://2015.igem.org/Team:BGU_Israel">Home</a></li> | | <li><a id="home" href="https://2015.igem.org/Team:BGU_Israel">Home</a></li> |
| <li><a id="A2" href="https://2015.igem.org/Team:BGU_Israel/Team">Team</a> | | <li><a id="A2" href="https://2015.igem.org/Team:BGU_Israel/Team">Team</a> |
− | <ul> <!-- optional --> | + | <!--<ul> optional |
| <li><a href="https://2013.igem.org/Team:BGU_Israel/Team/Members">Members</a></li> | | <li><a href="https://2013.igem.org/Team:BGU_Israel/Team/Members">Members</a></li> |
| <li><a href="https://2013.igem.org/Team:BGU_Israel/Team/Sponsors">Sponsors</a></li> | | <li><a href="https://2013.igem.org/Team:BGU_Israel/Team/Sponsors">Sponsors</a></li> |
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| <li><a href="https://2013.igem.org/Team:BGU_Israel/Team/Attributions">Attributions</a></li> | | <li><a href="https://2013.igem.org/Team:BGU_Israel/Team/Attributions">Attributions</a></li> |
| <li><a href="https://2013.igem.org/Team:BGU_Israel/Team/Judging">Judging</a></li> | | <li><a href="https://2013.igem.org/Team:BGU_Israel/Team/Judging">Judging</a></li> |
− | </ul> | + | </ul> --> |
| </li> | | </li> |
| | | |
| <li>Project | | <li>Project |
| <ul> | | <ul> |
− | <li><a id="A1" href="https://2015.igem.org/Team:BGU_Israel/Description">Description</a></li> | + | <li><a id="A3" href="https://2015.igem.org/Team:BGU_Israel/Description">Description</a></li> |
| <li> <a href="https://2015.igem.org/Team:BGU_Israel/Experiments">Experiments & Protocols</a> </li> | | <li> <a href="https://2015.igem.org/Team:BGU_Israel/Experiments">Experiments & Protocols</a> </li> |
| <li><a href="https://2015.igem.org/Team:BGU_IsraelResults">Results</></a> </li> | | <li><a href="https://2015.igem.org/Team:BGU_IsraelResults">Results</></a> </li> |
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| <li><a href="https://2015.igem.org/Team:BGU_Israel/Parts">Team Parts</a></li> | | <li><a href="https://2015.igem.org/Team:BGU_Israel/Parts">Team Parts</a></li> |
| <li><a href="https://2015.igem.org/Team:BGU_Israel/Basic_Part">Basic Parts</a> </li> | | <li><a href="https://2015.igem.org/Team:BGU_Israel/Basic_Part">Basic Parts</a> </li> |
− | <li><a href="https://2015.igem.org/Team:BGU_Israel/Composite_Part">Composite Parts</a></li> | + | |
| <li><a href="https://2015.igem.org/Team:BGU_Israel/Part_Collection">Part Collection</a> </li> | | <li><a href="https://2015.igem.org/Team:BGU_Israel/Part_Collection">Part Collection</a> </li> |
| </ul> | | </ul> |
| </li> | | </li> |
| | | |
− | <li><a id="A3" href="https://2015.igem.org/Team:BGU_Israel/Notebook">Notebook</a></li> | + | <li><a id="A4" href="https://2015.igem.org/Team:BGU_Israel/Notebook">Notebook</a></li> |
| | | |
| <li> MORE | | <li> MORE |
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| <li> <a href="https://2015.igem.org/Team:BGU_Israel/Practices">Human practices</a></li> | | <li> <a href="https://2015.igem.org/Team:BGU_Israel/Practices">Human practices</a></li> |
| <li> <a href="https://2015.igem.org/Team:BGU_Israel/Safety">Safety</a></li> | | <li> <a href="https://2015.igem.org/Team:BGU_Israel/Safety">Safety</a></li> |
− | <li> <a href="https://2015.igem.org/Team:BGU_Israel/Modeling">Modeling</a></li>
| + | |
− | <!-- <li> <a href="https://2015.igem.org/Team:BGU_Israel/Measurement">MEASUREMENT</a></li> | + | |
− | <!-- <a href="https://2015.igem.org/Team:BGU_Israel/Software"><li>SOFTWARE</li></a> -->
| + | |
| <li> <a href="https://2015.igem.org/Team:BGU_Israel/Entrepreneurship">Entrepreneurship</a></li> | | <li> <a href="https://2015.igem.org/Team:BGU_Israel/Entrepreneurship">Entrepreneurship</a></li> |
| | | |
| </ul> | | </ul> |
| </li> | | </li> |
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| </p> | | </p> |
| <div id="wikicontent-container"> | | <div id="wikicontent-container"> |
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− | <li><img src="https://static.igem.org/mediawiki/2015/2/26/BGU_home_slider_team1.jpg" /></li>
| + | |
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− | <li><img src="https://static.igem.org/mediawiki/2015/6/6a/BGU_home_slider_team5.jpg" /></li>
| + | |
− | </ul>
| + | |
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| + | <br /><br /> |
− |
| + | |
− | <div style="height: 145px; margin: 5px 0px 5px;"> | + | |
− | <table style="width: 100%; border-style: hidden;" >
| + | |
− | <tr style="border-style: hidden;">
| + | |
− | <td style="border-style: hidden;"><a href="https://2015.igem.org/Team:BGU_Israel/Entrepreneurship" class="rotate"><img src="https://static.igem.org/mediawiki/2015/b/b9/BGU_home_icon_briefcase.png" alt=""></a></td>
| + | |
− | <td style="border-style: hidden;"><a href="https://2015.igem.org/Team:BGU_Israel/Entrepreneurship" class="rotate"><img src="https://static.igem.org/mediawiki/2015/b/b9/BGU_home_icon_briefcase.png" alt=""></a></td>
| + | |
− | <td style="border-style: hidden;"><a href="https://2015.igem.org/Team:BGU_Israel/Entrepreneurship" class="rotate"><img src="https://static.igem.org/mediawiki/2015/b/b9/BGU_home_icon_briefcase.png" alt=""></a></tdstyle="border-style:>
| + | |
− | <td style="border-style: hidden;"><a href="https://2015.igem.org/Team:BGU_Israel/Entrepreneurship" class="rotate"><img src="https://static.igem.org/mediawiki/2015/b/b9/BGU_home_icon_briefcase.png" alt=""></a></td>
| + | |
− | <td style="border-style: hidden;"><a href="https://2015.igem.org/Team:BGU_Israel/Entrepreneurship" class="rotate"><img src="https://static.igem.org/mediawiki/2015/b/b9/BGU_home_icon_briefcase.png" alt=""></a></td>
| + | |
− | </tr>
| + | |
− | <tr style="border-style: hidden;">
| + | |
− | <td style="text-align: left; border-style: hidden;"> Entrepreneurship</td>
| + | |
− | <td style="text-align: left; border-style: hidden;"> Safety</td>
| + | |
− | <td style="text-align: left; border-style: hidden;"> Judging</td>
| + | |
− | <td style="text-align: left; border-style: hidden;"> Photos</td>
| + | |
− | <td style="text-align: left; border-style: hidden;"> Extra</td>
| + | |
− | </tr>
| + | |
| | | |
− | </table>
| + | <h2> Basic Parts</h2> |
− |
| + | |
− | <!-- <a href="https://2013.igem.org/Team:TU-Munich/Results/Economics" class="rotate"><img src="https://static.igem.org/mediawiki/2015/b/b9/BGU_home_icon_briefcase.png" alt=""></a>
| + | |
− | <a class="button application" href="https://2013.igem.org/Team:TU-Munich/Results/Implementation">Application</a>
| + | |
− | <a class="button autoannotator" href="https://2013.igem.org/Team:TU-Munich/Results/AutoAnnotator">AutoAnnotator</a>
| + | |
− |
| + | |
− | <a class="button physco" href="https://2013.igem.org/Team:TU-Munich/Project/Physcomitrella">Physco</a>
| + | |
− | <a class="button safety" href="https://2013.igem.org/Team:TU-Munich/Project/Safety">Safety</a>
| + | |
− | <a class="button judging" href="https://2013.igem.org/Team:TU-Munich/Team/Judging">Judging</a> -->
| + | |
− | </div>
| + | |
− | | + | |
− | <h2> <span class="mw-headline" id="PhyscoFilter_.E2.80.93_Clean_different."> Cancer – what is the problem? </span></h2> | + | |
− | <p>Despite the huge investment in research and the development of a variety of treatment methods, cancer is still a major cause of death in the world.
| + | |
− | <br /> Today, both surgical and pharmacological treatments against most types of cancer are not accurate enough to identify and treat the disease on a cellular level.
| + | |
− | On the other hand, novel biological treatments being developed were only found effective for a relatively small number of patients.
| + | |
− | <br />In cancer, many cellular and molecular processes take place, enabling the tumor to develop and spread in the body.
| + | |
− | <br />We believe that it is possible to take advantage of the many typical biological mechanisms of cancer cells, by developing a synthetic biology-based system for identifying and treating cancer on a cellular level.
| + | |
− | Together as a team, we developed a modular system which identifies numerous genetic changes in cancer cells and responds by activating a synthetic machine that executes a cell suicide program or enables color-based "tagging" of the cells for tumor detection, ensuring complete surgical removal.</p>
| + | |
| | | |
− | | + | <table width=90% align=center class="parts"> |
− |
| + | <tr><br><br><br> |
− | <!-- movie -->
| + | <td><h3><b>PART NAME</b></h3></td> |
− | <right><iframe style="box-shadow: 1px 1px 2px rgba(0, 0, 0, 0.2);padding: 5px;margin: 5px;background-color: white;" src="http://player.vimeo.com/video/110058399" width="900" height="510" frameborder="0" webkitAllowFullScreen mozallowfullscreen allowFullScreen></iframe></right>
| + | <td><h3><b>PART NUMBER</b></h3></td> |
− | </p> | + | |
| | | |
| + | </tr> |
| | | |
| + | <!--0--> |
| + | <tr> |
| + | <td>Human short TERT promoter</td> |
| + | <td><a href="http://parts.igem.org/Part:BBa_K1699001"> Part:BBa_K1699001</a></td> |
| + | </tr> |
| | | |
| + | <tr> |
| + | <td>gRNA for SaCas9 targeting ubiquitin B</td> |
| + | <td><a href="http://parts.igem.org/Part:BBa_K1699002"> Part:BBa_K1699002 </a></td> |
| + | </tr> |
| | | |
− | <!-- achivments --> | + | <!--1--> |
| + | <tr> |
| + | <td> gRNA for dCas9-VP64 targeting synthetic activation promoter pMLPm</td> |
| + | <td><a href="http://parts.igem.org/Part:BBa_K1699003"> Part:BBa_K1699003 </a></td> |
| + | </tr> |
| | | |
− | <h2> <span class="mw-headline" id="Achievements"> Achievements </span></h2> | + | <tr> |
− | <p><div class="thumb tright" id="blubberkolben"> | + | <td>gRNA for SaCas9 targeting ubiquitin B under U6 promoter</td> |
− | <div class="thumbinner" style="width:400px;">
| + | <td><a href="http://parts.igem.org/Part:BBa_K1699004"> Part:BBa_K1699004 </a></td> |
− | <a href="/File:TUM13_blubbern-stop.gif" class="image">
| + | </tr> |
− | <img alt="" src="https://static.igem.org/mediawiki/2013/a/ab/TUM13_blubbern-stop.gif" width="400" class="thumbimage" />
| + | |
− | </a>
| + | |
− | <div class="thumbcaption">
| + | |
− | <div class="magnify">
| + | |
− | <a href="/File:TUM13_Physco-lifecycle.png" class="internal" title="Enlarge">
| + | |
− | <img src="/wiki/skins/common/images/magnify-clip.png" width="15" height="11" alt="" />
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− | </a>
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− | Hover over the picture!<br />Then you can actually <b>HEAR</b> the sound in our laboratory.
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− | <div class="achievements">
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− | <h4> <span class="mw-headline" id="European_Jamboree_results:"> European Jamboree <a href="https://igem.org/Results?year=2013&region=All&division=igem" class="external text" rel="nofollow">results</a>: </span></h4>
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− | <ul><li> Gold medal
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− | </li><li> Best Wiki
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− | </li><li> European First Runner Up
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− | </li></ul>
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− | <h4> <span class="mw-headline" id="World_Jamboree_results:"> World Jamboree <a href="https://igem.org/Results?year=2013&region=All&division=igem" class="external text" rel="nofollow">results</a>: </span></h4>
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− | <ul><li> Best Environment Project
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− | </li><li> World First Runner Up
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− | </li></ul>
| + | |
− | <h4> <span class="mw-headline" id="Business_plan_competitions_after_iGEM:"> Business plan competitions after iGEM: </span></h4>
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− | <ul><li> 1<sup>st</sup> place at the <a href="http://www.tum.de/die-tum/aktuelles/pressemitteilungen/kurz/article/31350/" class="external text" rel="nofollow">TUM IdeAward</a>
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− | </li><li> 2<sup>nd</sup> place at the <a href="http://www.presseportal.de/print/2731699-projekt-zum-internet-der-dinge-gewinnt-hochschulwettbewerb-der.html" class="external text" rel="nofollow">Be.Project Competition</a>
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− | </li><li> 3<sup>rd</sup> place in the second round of the <a href="http://www.tum.de/wirtschaft/entrepreneurship/entrepreneurship-news/artikel/article/31515/" class="external text" rel="nofollow">Munich Business Plan Competition</a>
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| + | <tr> |
| + | <td>gRNA for dCas9-VP64 targeting synthetic activation promoter pMLPm under U6 promoter</td> |
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− | <a id="youtube" href="http://player.vimeo.com/video/110058399" target="blank"></a> | + | <a id="youtube" href="https://www.youtube.com/watch?v=B8qtBpE3RDE" target="blank"></a> |
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− | <div id="address">
| |
− | <h2>Address:</h2>
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− | <p>iGEM Team BGU-ISRAEL<br />
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− | <p>Email: <a id="A4" href="mailto:igembgu2015@gmail.com">igembgu2015@gmail.com</a><br />
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− | Phone: +972 52 332 2412</p>
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− | </div>
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| + | <div id="Div3"> |
| + | <h2>Address:</h2> |
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