Difference between revisions of "Team:Freiburg/Home"

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             <div class="cool_header"><a href='#'>Own Device</a></div>
 
             <div class="cool_header"><a href='#'>Own Device</a></div>
 
           <div class="cool_image_blink element1">
 
           <div class="cool_image_blink element1">
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             <div class="cool_content cool_text_blink">Want to use our detection device in your next iGEM project? We built our own simplified and affordable setup. Here you can find a detailed description of how to build and use it.</div>
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             <div class="cool_content cool_text_blink">We built our own simplified and affordable detection device. Check out the step by step instructions !</div>
 
           </div>
 
           </div>
 
         </li>
 
         </li>
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           <div class="cool_header"><a href='#'>New iGEM Backbone</a></div>
 
           <div class="cool_header"><a href='#'>New iGEM Backbone</a></div>
 
           <div class="cool_image_blink element2">
 
           <div class="cool_image_blink element2">
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           <div class="cool_content cool_text_blink">In need for expressing tons of protein? We provided a new backbone for protein overexpression meeting all the iGEM standards. We also expanded the iGEM Registry with our </div>
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           <div class="cool_content cool_text_blink">We provided a new backbone for protein overexpression meeting all the iGEM standards. <br> See how we epanded the iGEM registry!</div>
 
           </div>
 
           </div>
 
         </li>
 
         </li>
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           <div class="cool_header"><a href='#'>Human Practice</a></div>
 
           <div class="cool_header"><a href='#'>Human Practice</a></div>
 
           <div class="cool_image_blink element3">
 
           <div class="cool_image_blink element3">
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           <div class="cool_content cool_text_blink">What does the public think about the DiaCHIP and systems based on synthetic biology? Would people want to use it? Check out the results of our survey.</div>
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           <div class="cool_content cool_text_blink">What do people think about the DiaCHIP and systems based on synthetic biology? <br> Check out the results of our survey and discussions !</div>
 
           </div>
 
           </div>
 
         </li>
 
         </li>
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           <div class="cool_header"><a href='#'>Modeling</a></div>
 
           <div class="cool_header"><a href='#'>Modeling</a></div>
 
           <div class="cool_image_blink element4">
 
           <div class="cool_image_blink element4">
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           <div class="cool_content cool_text_blink">Numerous complex processes take place during cell-free expression. Modeling the generation of proteins as well as their diffusion in our system helped us obtaining better results. Get more information here.</div>
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           <div class="cool_content cool_text_blink">Modeling the generation of proteins during cell-free expression as well as their diffusion in our system helped us obtaining better results. Get more information here.</div>
 
           </div>
 
           </div>
 
         </li>
 
         </li>
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             <div class="cool_header"><a href='#'>Blood Serum Analysis</a></div>
 
             <div class="cool_header"><a href='#'>Blood Serum Analysis</a></div>
 
           <div class="cool_image_blink element5">
 
           <div class="cool_image_blink element5">
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             <div class="cool_content cool_text_blink">We obtained great results during summer! Our successful measurements of tetanus antibodies in human serum and GFP antibodies binding to cell-free expressed GFP can be found on our results page.</div>
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             <div class="cool_content cool_text_blink">We successfully detected tetanus antibodies in human blood serum and measured binding of GFP antibodies to cell-free expressed GFP. <br> Visit our results page !</div>
 
           </div>
 
           </div>
 
         </li>
 
         </li>
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         <li><!--6-->
 
         <li><!--6-->
  
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             <div class="cool_header"><a href='#'>Enlightening Diagnostics</a></div>
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             <div class="cool_header"><a href='#'>Diagnostics today</a></div>
 
           <div class="cool_image_blink element6">
 
           <div class="cool_image_blink element6">
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             <div class="cool_content cool_text_blink">Modern everyday life is fast...too fast for medical diagnosis relying on huge amounts of time-consuming and costly serological tests.
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             <div class="cool_content cool_text_blink">Nowadays, medical diagnosis is mainly based on huge amounts of time-consuming and costly serological tests.
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    This is why we thought about a fast, universally accessible and affordable diagnostic device.</div>
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  Read more about the issues we tackled !</div>
 
           </div>
 
           </div>
 
         </li>
 
         </li>
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             <div class="cool_header"><a href='#'>The DiaCHIP</a></div>
 
             <div class="cool_header"><a href='#'>The DiaCHIP</a></div>
 
           <div class="cool_image_blink element7">
 
           <div class="cool_image_blink element7">
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             <div class="cool_content cool_text_blink">Simultaneously screening for hundreds of diseases within a few hours? See how the DiaCHIP achieves this by the revolutionary combination of cell-free expression with an emerging optical method allowing label-free antibody detection.</div>
+
             <div class="cool_content cool_text_blink">Simultaneously screening for hundreds of diseases within a few hours? <br> Find out about the DiaCHIP's potential to revolutionize future diagnostics !</div>
 
           </div>  
 
           </div>  
 
         </li>
 
         </li>
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             <div class="cool_header"><a href='#'>Our System</a></div>
 
             <div class="cool_header"><a href='#'>Our System</a></div>
 
           <div class="cool_image_blink element8">
 
           <div class="cool_image_blink element8">
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             <div class="cool_content cool_text_blink">Generating a protein array on demand and detecting antigen-antibody interactions in real-time: Find out about our own cell-free expression mix and our specific surface binding system.</div>
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             <div class="cool_content cool_text_blink">Generating a protein array on demand via cell-free expression and detecting antigen-antibody interactions label-free and in real-time: The principle behind the DiaCHIP !</div>
 
           </div>
 
           </div>
 
         </li>
 
         </li>

Revision as of 11:36, 13 September 2015

""

  • Own Device
    We built our own simplified and affordable detection device. Check out the step by step instructions !
  • New iGEM Backbone
    We provided a new backbone for protein overexpression meeting all the iGEM standards.
    See how we epanded the iGEM registry!
  • Human Practice
    What do people think about the DiaCHIP and systems based on synthetic biology?
    Check out the results of our survey and discussions !
  • Modeling
    Modeling the generation of proteins during cell-free expression as well as their diffusion in our system helped us obtaining better results. Get more information here.
  • Blood Serum Analysis
    We successfully detected tetanus antibodies in human blood serum and measured binding of GFP antibodies to cell-free expressed GFP.
    Visit our results page !
  • Diagnostics today
    Nowadays, medical diagnosis is mainly based on huge amounts of time-consuming and costly serological tests. Read more about the issues we tackled !
  • The DiaCHIP
    Simultaneously screening for hundreds of diseases within a few hours?
    Find out about the DiaCHIP's potential to revolutionize future diagnostics !
  • Our System
    Generating a protein array on demand via cell-free expression and detecting antigen-antibody interactions label-free and in real-time: The principle behind the DiaCHIP !

DiaCHIP - Enlightening Diagnostics

In modern medicine, fast detection and differentiation of diseases is a crucial and fundamental task. Typical ELISA-based assays are time-consuming and expensive. We propose an advanced procedure for the simultaneous detection of various diseases in a fast and inexpensive manner, the DiaCHIP. Our approach is based on the interaction of antibodies with their respective antigens. Different antigens are immobilized on a protein array generated by cell-free protein expression, using the corresponding DNA array as a template. Placed in a microfluidic chamber, the protein array is incubated with a patient’s blood sample. The interaction between an antibody in the sample and the corresponding immobilized antigen results in a local change of the optical thickness of the surface. This change can be detected using a label-free and real-time measurement technology called iRIf (imaging Reflectometric Interference). Offering simultaneous screening for several diseases, our DiaCHIP has strong potential to improve future diagnostics.