Difference between revisions of "Team:Freiburg/Project/Overview"
Line 26: | Line 26: | ||
h1 { | h1 { | ||
text-align: center; | text-align: center; | ||
+ | color: #888; | ||
+ | font-size: 300%; | ||
+ | text-shadow: | ||
+ | 1px 0px 1px #ccc, 0px 1px 1px #eee, | ||
+ | 2px 1px 1px #ccc, 1px 2px 1px #eee, | ||
+ | 3px 2px 1px #ccc, 2px 3px 1px #eee, | ||
+ | 4px 3px 1px #ccc, 3px 4px 1px #eee, | ||
+ | 5px 4px 1px #ccc, 4px 5px 1px #eee, | ||
+ | 6px 5px 1px #ccc, 5px 6px 1px #eee, | ||
+ | 7px 6px 1px #ccc; | ||
} | } | ||
Line 32: | Line 42: | ||
padding: 2% 0%; | padding: 2% 0%; | ||
margin: auto; | margin: auto; | ||
− | width: | + | width: 70%; |
text-align: left; | text-align: left; | ||
− | background-color: #FFF; | + | /*background-color: #FFF; |
border-radius: 30px 60px; | border-radius: 30px 60px; | ||
box-shadow: 1px 1px 10px #888; | box-shadow: 1px 1px 10px #888; | ||
-webkit-box-shadow: 1px 1px 10px #888; | -webkit-box-shadow: 1px 1px 10px #888; | ||
− | -moz-box-shadow: 1px 1px 10px #888; | + | -moz-box-shadow: 1px 1px 10px #888;*/ |
} | } | ||
Revision as of 15:41, 14 September 2015
![](https://static.igem.org/mediawiki/2015/8/85/Freiburg_wiki_background_2_parted_left.png)
![](https://static.igem.org/mediawiki/2015/f/f4/Freiburg_wiki_background_2_parted_right.png)
The DiaCHIP - A Versatile Detection System
![DiaCHIP_Sabi](https://static.igem.org/mediawiki/2015/a/af/Freiburg_DiaCHIP_Sabi.png)
Project Motivation
Serological tests are a key element in modern medicine. Especially, when it comes to the detection and identification of infectious diseases performing different blood tests is inevitable. Regardless if a patient has diffuse symptoms or if he is tested for a defined number of diseases, more than one serological test has to be performed each time. Many tests, many days of waiting and an increasing bill: With some infectious diseases every minutes counts and not everyone can afford a long series of testing. What if there was a possibility to combine all tests in one single affordable device?
Detecting Antigen-Antibody Interactions
The DiaCHIP is an innovative tool to screen for a broad range of antibodies present in serum.
Antibodies can be an indicator for an immune response towards an infection or a successful vaccination.
Antibodies also play a role in the diagnosis of autoimmune diseases.
Especially the ability to differentiate between life threatening diseases and a mild infection within a short time bears the potential to save lives.
Spotting diseases by detecting correspondent antibodies in a patient's serum is an established method in modern diagnostics. The DiaCHIP makes it possible to screen for multiple specific antibodies simply using a drop of blood.
The Concept
The key feature of the DiaCHIP concept is the combination of on-demand protein synthesis and a novel method for label-free detection packed into one device. The idea is to overcome challenges commonly found in protein array production and preservation. In addition, results can be obtained in a time- and cost-efficient manner; with a device simple enough to be rebuilt by future iGEM teams.