Difference between revisions of "Team:San Andres/Description"

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<h2> Project Description </h2>
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<p> Our project is about the celiac disease, a enteropathy, autoimmune affecting individuals who possess genes HLA-DQ8 or HLA-DQ2, where T cells attack the body when the gliadins and glutenins are absorbed by the small intestine, in others words, celiac patients have a permanent intolerance to gluten-containing foods.
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[[File:ID 800.jpg]]
  
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<p>Tell us about your project, describe what moves you and why this is something important for your team.</p>
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When the gluten to come into contact with the villi of the small intestine (enterocytes), the cells helper (type of reporter) detected the gluten like as a toxic substance and leave a footprint chemistry, which is followed by antibodies and lymphocytes T and B. The first are the natural killer and an army of these cells attack the infected cells, which could cause a carcinogen effect, in this case the dangerous cells are the enterocytes, causing inflammation, poor absorption, and other symptoms.
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<h5>What should this page contain?</h5>
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The damage caused by the autoimmune reaction can cause histological damage in the villi, and a biopsy of these is the means of diagnosis of this pathology. The only current treatment is a diet without gluten, which is expensive and difficult to follow.
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<li> A clear and concise description of your project.</li>
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<li>A detailed explanation of why your team chose to work on this particular project.</li>
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<li>References and sources to document your research.</li>
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<li>Use illustrations and other visual resources to explain your project.</li>
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<h4>Advice on writing your Project Description</h4>
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We encourage you to put up a lot of information and content on your wiki, but we also encourage you to include summaries as much as possible. If you think of the sections in your project description as the sections in a publication, you should try to be consist, accurate and unambiguous in your achievements.
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Judges like to read your wiki and know exactly what you have achieved. This is how you should think about these sections; from the point of view of the judge evaluating you at the end of the year.
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<h4>References</h4>
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<p>iGEM teams are encouraged to record references you use during the course of your research. They should be posted somewhere on your wiki so that judges and other visitors can see how you though about your project and what works inspired you.</p>
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<h4>Inspiration</h4>
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<p>See how other teams have described and presented their projects: </p>
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<li><a href="https://2014.igem.org/Team:Imperial/Project"> Imperial</a></li>
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<li><a href="https://2014.igem.org/Team:UC_Davis/Project_Overview"> UC Davis</a></li>
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<li><a href="https://2014.igem.org/Team:SYSU-Software/Overview">SYSU Software</a></li>
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Revision as of 14:09, 20 June 2015




Indian Institute of Science Education and Research (IISER), Pune, India

Our project is about the celiac disease, a enteropathy, autoimmune affecting individuals who possess genes HLA-DQ8 or HLA-DQ2, where T cells attack the body when the gliadins and glutenins are absorbed by the small intestine, in others words, celiac patients have a permanent intolerance to gluten-containing foods. ID 800.jpg When the gluten to come into contact with the villi of the small intestine (enterocytes), the cells helper (type of reporter) detected the gluten like as a toxic substance and leave a footprint chemistry, which is followed by antibodies and lymphocytes T and B. The first are the natural killer and an army of these cells attack the infected cells, which could cause a carcinogen effect, in this case the dangerous cells are the enterocytes, causing inflammation, poor absorption, and other symptoms. Scd 800.jpg The damage caused by the autoimmune reaction can cause histological damage in the villi, and a biopsy of these is the means of diagnosis of this pathology. The only current treatment is a diet without gluten, which is expensive and difficult to follow. HS 400.jpgSG 400.jpg