Difference between revisions of "Team:Stony Brook"

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<h4>Background</h4>
 
<p> The human body has many feedback systems to maintain a suitable environment for its cells.  In its simplest form, a homeostatic system consists of a sensor and a response that the sensor can trigger.  Our project investigates recreating such a system using E. Coli to determine the robustness and reliability of such an endeavor.  Our project has its roots in type II diabetes, when we thought about how people with this disease cannot get rid of excess glucose in their blood naturally.  We imagined a system in which E. Coli detect high levels of glucose, and help the human body eliminate it.  Most importantly, we decided to try and do this without the use of insulin in any way, due to the insulin insensitivity of the afflicted.</p>
 
<p> The human body has many feedback systems to maintain a suitable environment for its cells.  In its simplest form, a homeostatic system consists of a sensor and a response that the sensor can trigger.  Our project investigates recreating such a system using E. Coli to determine the robustness and reliability of such an endeavor.  Our project has its roots in type II diabetes, when we thought about how people with this disease cannot get rid of excess glucose in their blood naturally.  We imagined a system in which E. Coli detect high levels of glucose, and help the human body eliminate it.  Most importantly, we decided to try and do this without the use of insulin in any way, due to the insulin insensitivity of the afflicted.</p>
  

Revision as of 18:12, 4 August 2015

Stony Brook iGEM 2015


Project Description