Team:Freiburg/Home

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Die Texte in den Boxen sind noch ziemlich klein und ziemlich Textwand. Da müssten kürzere, prägnantere Texte mit größerer Schrift und/oder Bild rein. (jb 20150912)

Texte sind zum Überarbeiten. Maximale Länge von 6 Zeilen ist optisch am besten. Die Texte sollen hinter Bildern "versteckt werden". Der Text erscheint, dann erst, wenn man mit dem Mauszeiger über das Bild fährt. - Das ist zumindest der Plan, arbeite noch an den Bildern - (sb 20150912)

find ich gut soweit, bin gespannt wie es fertig aussieht (NG)

Abstract

In modern medicine, fast detection and differentiation of diseases is a crucial and fundamental task. Typical ELISA-based assays are time-consuming and expensive. We propose an advanced procedure for the simultaneous detection of various diseases in a fast and inexpensive manner, the DiaCHIP. Our approach is based on the interaction of antibodies with their respective antigens. Different antigens are immobilized on a protein array generated by cell-free protein expression, using the corresponding DNA array as a template. Placed in a microfluidic chamber, the protein array is incubated with a patient’s blood sample. The interaction between an antibody in the sample and the corresponding immobilized antigen results in a local change of the optical thickness of the surface. This change can be detected using a label-free and real-time measurement technology called iRIf (imaging Reflectometric Interference)which is based on a laser detecting the interference of reflecting light from our chip. Offering simultaneous screening for several diseases, our DiaCHIP has strong potential to improve future diagnostics.