Team:ETH Zurich/Achievements
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Practices - Parts
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Achievements
We are proud to announce that we achieved the following goals
General Achievements
- We designed a novel system for detection of circulating tumour cells in blood samples using genetically modified bacteria.
- We designed a genetic circuit that integrates two different cancer specific signals (lactate and AHL)in an AND gate.
- We implemented a method to do single cell analysis of cancer cells by expressing Annexin V on the E. coli membrane that makes them stick to apoptotic mammalian cells.
Experimental Achievements
- We characterized parts of the natural E. coli lldPRD-operon, on which there is only a very limited amount of information present in the literature.
- We designed x synthetic lldR dependent promoters and characterized them (additionally the influence of the lacate importer llDP was characterized)
- We documented and submitted XX new basic parts to the iGEM parts registry and created a part collection with XX parts.
- We designed a chip for later easy application of our MicroBeacon E. coli.
- We participated in the interlab study.
- We attended the safety instrucions from the department D-BSSE in basel where we have our lab.
Modeling Achievements
- By modeling the system we showed that the system as a whole can work.
Human Practices Achievements
- We collaborated with the team from Stockholm by testing some of their constructs.
- We contributed to the Newsletters from Amoys team, met with the Darmstadt team, helped with a survey from EPFL and provided Colombias team with protocols and advice when their transformations did not work.
- We interviewed many different experts from various fields, such as medical doctors, somebody from the ethics commission, the founder of a start-up or an expert in patents law and integrated the advice and ideas we got from them into the design.
- We went to two different schools, thaught the children about what DNA is, performed experiments with them and published an article about it in the local newspaper.
- We told the ETH-student magacine polykum about iGEM and gave an interview.