Team:ETH Zurich/Achievements
- Project
- Modeling
- Lab
- Human
Practices - Parts
- About Us
Achievements
We are proud to announce that we achieved the following goals
General Achievements
- We completed the Judging Form
- We created a description of our project in time and documented each aspect of the project on this page.
- Documented 20 parts taken from the Registry of Standard Biological Parts.
Experimental Achievements
- We designed a novel system for detection of circulating tumour cells in blood samples using genetically modified bacteria.
- We designed a genetic circuit that integrates two different cancer specific signals (lactate and AHL)in an AND gate.
- We implemented a method to do single cell analysis of cancer cells by expressing Annexin V in the E. coli outer membrane, which enables them to selectively bind to apoptotic cancer cells.
- We designed 8 synthetic LldR dependent promoters and characterized them. Additionally, the influence of the lacate importer LldP was characterized.
- We characterized parts of the natural E. coli lldPRD-operon, on which there is only a very limited amount of information present in the literature.
- We documented and submitted two new basic parts to the iGEM parts registry and created a part collection with 14 parts.
- We designed a chip for later easy application of our MicroBeacon E. coli.
- We participated in the interlab study.
- Our experiments complied with the safety instructions at the Department of Biosystems Science and Engineering D-BSSE in Basel where our lab is situated.
Modeling Achievements
- By modeling the system we showed that the system as a whole can work.
Human Practices Achievements
- We went to two different schools, thaught the children about what DNA is, performed experiments with them and published an article about it in the local newspaper.
- We told the ETH-student magacine polykum about iGEM and gave an interview.
- We collaborated with the team from Stockholm by testing some of their constructs.
- We contributed to the Newsletters from Amoys team, met with the Darmstadt team, helped with a survey from EPFL and provided Colombias team with protocols and advice when their transformations did not work.
- We interviewed many different experts from various fields, such as medical doctors, somebody from the ethics commission, the founder of a start-up or an expert in patents law and integrated the advice and ideas we got from them into the design.