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Revision as of 12:40, 25 August 2015

Application

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Crowdfunding

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Safety

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Judging

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Controlling the lifetime of GMOs using ColiClock

As you may know, there is worldwide concern related to the issue of genetically modified organisms uncontrolled spreading in natural environment. We are heading forward to design bacteria aging system using CRISPR/Cas3. This built in bacteria “clock” would allow us to control how long genetically modified bacteria will survive outside laboratory.
Our system consists of two plasmids. One controlling repression of CRISPR/Cas3 complex, and another containing CRISPR/Cas3 complex itself. Outside laboratory there is no chemical compounds controlling repression of CRISPR/Cas3 complex, so bacteria DNA is degraded. By changing repression level we aim to manipulate and control how long such bacteria can survive in natural environment.
Our project is under construction, so visit us for updates.

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