Difference between revisions of "Team:Vilnius-Lithuania/Application"

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       <p class="text-justify">Many iGEM projects, associated with some kind of material degradation, are based on the idea that bacteria only lives, when there is enough food around it. For example, oil decomposing bacteria dies, when there is scarcity of an oil around. But this system is not 100% safe. Bacteria does not have a system that prevents accidental spreading. Our system can be a solution.</p>
 
       <p class="text-justify">Many iGEM projects, associated with some kind of material degradation, are based on the idea that bacteria only lives, when there is enough food around it. For example, oil decomposing bacteria dies, when there is scarcity of an oil around. But this system is not 100% safe. Bacteria does not have a system that prevents accidental spreading. Our system can be a solution.</p>
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      <p class="text-justify">This year Pasteur Paris team created a project, called <a href="https://2015.igem.org/Team:Pasteur_Paris/Description" style="color:darkgreen">PlastiCure  </a>. Their method is able to decompose PET in seas and use following degradation products to synthesize bioactive compouds. In this case we can suggest our system. If we had incorporated Coliclock in Plasticure, it would become a safe solution to world oceans.</p>
  
 
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Revision as of 02:42, 15 September 2015

Coliclock application

Generally speaking, Coliclock system controls the lifetime of GMOs in the environment. But further than that, our team was interested in some more specific applications. We chose to analyze previous and this year's iGEM projects and tried to theoretically incorporate our system in their genetically engineered bacteria.

Bee. coli

First project that we were interested in, was 2013 Taipei team’s Bee. coli project. This team suggested light induced system to prevent the spreading of bacteria. According to their data and experiment, this system works in vitro in a lab environment. If we think about this kind of bacteria live in bees, it’s easy to imagine that bacteria can spread in the dark and get into other species.

If we added our Coliclock system into Bee. coli, bacteria would produce proteins against Nosema ceranae, parazite, which affects bees and causes them to get sick. In theory, Bee. coli project would ne responsible for the protein system, whilst our construct, Coliclock would be responsible for the time of the performed function. Cells divide for some time and then die. Regulation of light is not essential here and bacteria will back out on its own.

PlastiCure

Many iGEM projects, associated with some kind of material degradation, are based on the idea that bacteria only lives, when there is enough food around it. For example, oil decomposing bacteria dies, when there is scarcity of an oil around. But this system is not 100% safe. Bacteria does not have a system that prevents accidental spreading. Our system can be a solution.

This year Pasteur Paris team created a project, called PlastiCure . Their method is able to decompose PET in seas and use following degradation products to synthesize bioactive compouds. In this case we can suggest our system. If we had incorporated Coliclock in Plasticure, it would become a safe solution to world oceans.