Difference between revisions of "Team:Paris Bettencourt"

 
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  <h3>Overview</h3>
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<h1>FIY - Ferment It Yourself!</h1><br/>
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Fermented foods form an integral part of various cultures all over the world. They were accepted as high nutrition foods long before we knew what microbes are or how fermentation works. <br/>
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<b>Food fermentation</b> is practiced by every culture in the world.
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Foods made out of fermented rice are staples in almost all of South India and Sri Lanka, with idli and dosa being over the most widely consumed throughout the Indian subcontinent.  
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It is especially widespread throughout the Indian subcontinent. Although fermentation enriches foods with some essential vitamins and amino acids, many regions of the subcontinent still suffer from high malnutrition. We are addressing this problem by engineering <i>S. cerevisiae</i> and lactobacilli, commonly found in Indian fermented rice dishes, to enrich foods with vitamins A, B2, and B12, and bioavailable iron.
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While the process of fermentation in the preparation of these dishes already enriches these foods with some essential vitamins and amino acids, these regions still suffer from high levels of malnutrition. This is due to a heavy dependence on rice and a lack of other food sources, which itself stems from socioeconomic issues. <br/><br/>
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We also implemented a differentiation system for reducing the fitness cost of over-expression of multiple pathways, and an easy <i>E. coli</i> sensor for measuring vitamin concentration using a riboswitch.
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Our user-centered approach incorporates a low-cost and open hardware framework, both for growing and distributing starter cultures, and for quality control.<br/><br/>
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This will give the local affected populations power over their own food, as opposed to other GMO nutritional enrichment strategies, by allowing them to grow their own source of vitamins.
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We are trying to tackle this problem of malnutrition in the region, while celebrating the cultural heritage of fermented foods, by engineering yeast and bacteria which, when used for fermentation, will enrich the food with vitamins A, B2 and B12. We'll introduce and improve the pathways to synthesize those vitamins in S. Cerevisiae and Lactobacillus, which are commonly found in indian dishes made of fermented rice.<br/>
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Since these micro-organisms are easy to culture, our product will allow people to grow their own source of vitamins in their kitchen.<br/><br/>
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Here is how to contact us:<br/>
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<a href="https://www.facebook.com/ParisiGEM2013">Facebook</a><br/>
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<a href="https://www.twitter.com/iGEM_Paris">Twitter</a><br/>
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See you soon!
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<h2> Welcome to iGEM 2015! </h2>
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<p>Your team has been approved and you are ready to start the iGEM season! </p>
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<h4>Before you start: </h4>
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<p> Please read the following pages:</p>
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<ul>
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<li> <a href="https://2015.igem.org/Requirements">Requirements page </a> </li>
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<li> <a href="https://2015.igem.org/Wiki_How-To">Wiki Requirements page</a></li>
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<h4> Styling your wiki </h4>
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<p>You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.</p>
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<p>While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.</p>  
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  <div class="3u yellow"><a href="https://2015.igem.org/Team:Paris_Bettencourt/Background" title="Background">
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<span class="stretch">Background</span></a></div>
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  <div class="3u cyan"><a href="https://2015.igem.org/Team:Paris_Bettencourt/Design" title="Design">
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<span class="stretch">Design</span></a></div>
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  <div class="3u magenta"><a href="https://2015.igem.org/Team:Paris_Bettencourt/Practices" title="Project">
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<span class="stretch">Practices</span></a></div>
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  <div class="3u magenta"><a href="https://2015.igem.org/Team:Paris_Bettencourt/Safety" title="Safety">
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<span class="stretch">Safety</span></a></div>
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  <div class="3u yellow"><a href="https://2015.igem.org/Team:Paris_Bettencourt/Notebook" title="Notebook">
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<span class="stretch">Notebook</span></a></div>
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  <div class="3u cyan"><a href="https://2015.igem.org/Team:Paris Bettencourt/Team" title="Team">
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<span class="stretch">Team</span></a></div>
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<h4> Editing your wiki </h4>
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<p>On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world! </p>
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<p> <a href="https://2015.igem.org/wiki/index.php?title=Team:Paris_Bettencourt&action=edit"> Click here to edit this page! </a></p>
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<p>See tips on how to edit your wiki on the <a href="https://2015.igem.org/TemplatesforTeams_Code_Documentation">Template Documentation</a> page.</p>
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<h4>Templates </h4>
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<p> This year we have created templates for teams to use freely. More information on how to use and edit the templates can be found on the
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<a href="https://2015.igem.org/TemplatesforTeams_Code_Documentation">Template Documentation </a> page.</p>
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<h4>Tips</h4>
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<p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p>
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<li>State your accomplishments! Tell people what you have achieved from the start. </li>
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<li>Be clear about what you are doing and how you plan to do this.</li>
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<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
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<li>Make sure information is easy to find; nothing should be more than 3 clicks away.  </li>
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<li>Avoid using very small fonts and low contrast colors; information should be easy to read.  </li>
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<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="https://2015.igem.org/Calendar_of_Events">iGEM 2015 calendar</a> </li>
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<li>Have lots of fun! </li>
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</ul>
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<h4>Inspiration</h4>
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<p> You can also view other team wikis for inspiration! Here are some examples:</p>
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<li> <a href="https://2014.igem.org/Team:SDU-Denmark/"> 2014 SDU Denmark </a> </li>
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<li> <a href="https://2014.igem.org/Team:Aalto-Helsinki">2014 Aalto-Helsinki</a> </li>
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<li> <a href="https://2014.igem.org/Team:LMU-Munich">2014 LMU-Munich</a> </li>
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<li> <a href="https://2014.igem.org/Team:Michigan"> 2014 Michigan</a></li>
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<li> <a href="https://2014.igem.org/Team:ITESM-Guadalajara">2014 ITESM-Guadalajara </a></li>
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<li> <a href="https://2014.igem.org/Team:SCU-China"> 2014 SCU-China </a></li>
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<h4> Uploading pictures and files </h4>
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<p> You can upload your pictures and files to the iGEM 2015 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name. <br />
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When you upload, set the "Destination Filename" to <code>Team:YourOfficialTeamName/NameOfFile.jpg</code>. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)</p>
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<a href="https://2015.igem.org/Special:Upload">CLICK HERE TO UPLOAD FILES</a>
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Latest revision as of 14:54, 1 December 2015

Overview

Food fermentation is practiced by every culture in the world. It is especially widespread throughout the Indian subcontinent. Although fermentation enriches foods with some essential vitamins and amino acids, many regions of the subcontinent still suffer from high malnutrition. We are addressing this problem by engineering S. cerevisiae and lactobacilli, commonly found in Indian fermented rice dishes, to enrich foods with vitamins A, B2, and B12, and bioavailable iron. We also implemented a differentiation system for reducing the fitness cost of over-expression of multiple pathways, and an easy E. coli sensor for measuring vitamin concentration using a riboswitch. Our user-centered approach incorporates a low-cost and open hardware framework, both for growing and distributing starter cultures, and for quality control.

This will give the local affected populations power over their own food, as opposed to other GMO nutritional enrichment strategies, by allowing them to grow their own source of vitamins.

Background
Design
Practices
Safety
Notebook
Team