Difference between revisions of "Team:Paris Bettencourt/Project/VitaminB12"
| Line 5: | Line 5: | ||
<h2>Introduction</h2> | <h2>Introduction</h2> | ||
| − | Vitamin B12, or cobalamin, is a family of molecules that are involved in only two chemical reactions in humans. | + | <p>Vitamin B12, or cobalamin, is a family of molecules that are involved in only two chemical reactions in humans. |
However a cobalamin deficiency can lead to troubles related to nervous system, brain and formation of blood. | However a cobalamin deficiency can lead to troubles related to nervous system, brain and formation of blood. | ||
| − | Diseases related to low blood levels of cobalamin include fatigue, depression, low red blood cells level and even | + | Diseases related to low blood levels of cobalamin include fatigue, depression, low red blood cells level and even sensory loss and infertility. <br> |
| + | https://books.google.fr/books?id=b9ahvNjPFO8C&lpg=PA245&hl=fr&pg=PA246#v=onepage&q&f=false <br> | ||
| + | http://www.bmj.com/content/349/bmj.g5226.long <br> | ||
| + | </p> | ||
| + | |||
| + | <p> | ||
| + | |||
| + | </p> | ||
<hr> | <hr> | ||
Revision as of 17:10, 4 September 2015
Ferment It Yourself
iGEM Paris-Bettencourt 2O15
- Background
- Design
-
-
-
-
-
-
-
Background
Aims
Results
Cobalamin (vitamin B12) deficiency is widely spread in India, due to diet that is mostly vegetarian. We aimed at introducing a high-level cobalamin producer to the rice batter. Tadaa.
Introduction
Vitamin B12, or cobalamin, is a family of molecules that are involved in only two chemical reactions in humans. However a cobalamin deficiency can lead to troubles related to nervous system, brain and formation of blood. Diseases related to low blood levels of cobalamin include fatigue, depression, low red blood cells level and even sensory loss and infertility.
https://books.google.fr/books?id=b9ahvNjPFO8C&lpg=PA245&hl=fr&pg=PA246#v=onepage&q&f=false
http://www.bmj.com/content/349/bmj.g5226.long
Ideas
Express the cobalamin biosynthesis pathway in Lactobacillus plantarum
Make Lactobacillus reuteri express a lot of cobalamin
Metabolic engineering
The pseudo-cobalamin problem
Use Propionibacterium freudenreichii
Advices for other teams
Conclusion
Click here to see our solution!
