Difference between revisions of "Team:Paris Bettencourt/Project/VitaminB2"
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− | <h1 class="date one" id="overview"> | + | <h1 class="date one" id="overview">Motivation</h1> |
<p>Riboflavin derived coenzymes (FMN and FAD) are the cofactors of numerous oxydo-reduction enzymes and are also used in the energy transduction process. It is also used in antioxidative reactions and is required for the metabolism of several other vitamins.</p> | <p>Riboflavin derived coenzymes (FMN and FAD) are the cofactors of numerous oxydo-reduction enzymes and are also used in the energy transduction process. It is also used in antioxidative reactions and is required for the metabolism of several other vitamins.</p> | ||
<p>Riboflavin deficiency is a rampant problem in India. For socio-economic reasons, indians are not consuming riboflavin-rich food (dairy products, offal, eggs, almonds...). | <p>Riboflavin deficiency is a rampant problem in India. For socio-economic reasons, indians are not consuming riboflavin-rich food (dairy products, offal, eggs, almonds...). | ||
− | Only 13% of the households meet the riboflavin dietary requirements and more than 70% of women and children of low-income groups (2009 Indian Council of Medical Research report) and 66% of children from middle-income groups have biochemical evidence of riboflavin deficiency (S. Swaminathan & al., European J. Clin. Nut., 2013) | + | Only 13% of the households meet the riboflavin dietary requirements and more than 70% of women and children of low-income groups (2009 Indian Council of Medical Research report) and 66% of children from middle-income groups have biochemical evidence of riboflavin deficiency (S. Swaminathan & al., European J. Clin. Nut., 2013).</p> |
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<p>The most recognizable manifestation of advanced riboflavin deficiency are orolingual, dermal, corneal and hematological.<br> | <p>The most recognizable manifestation of advanced riboflavin deficiency are orolingual, dermal, corneal and hematological.<br> | ||
In earlier stages, riboflavin deficiency decreases psychomotor abilities, induces fatigue as well as itching and burning in the eyes.During pregnancy, a riboflavin deficiency can lead to limb-reduction in infants (M. S. Bamji et al., Bulletin of Nutrition Foundation of India, 1993).</p> | In earlier stages, riboflavin deficiency decreases psychomotor abilities, induces fatigue as well as itching and burning in the eyes.During pregnancy, a riboflavin deficiency can lead to limb-reduction in infants (M. S. Bamji et al., Bulletin of Nutrition Foundation of India, 1993).</p> | ||
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+ | <h1 class="date one" id="design">Design</h1> | ||
<p>Riboflavin is synthesized by Plants, Bacteria and Fungi. Two fungi, <i>Ashbya gossypii</i> and <i>Candida famata</i> and a Gram positive bacteria, <i>Bacillus subtilis</i> are industrially used as riboflavin overproducers (K.-P Stahmann & <i>al</i>, Appl Micr. Biotech., 2000).</p> | <p>Riboflavin is synthesized by Plants, Bacteria and Fungi. Two fungi, <i>Ashbya gossypii</i> and <i>Candida famata</i> and a Gram positive bacteria, <i>Bacillus subtilis</i> are industrially used as riboflavin overproducers (K.-P Stahmann & <i>al</i>, Appl Micr. Biotech., 2000).</p> |
Revision as of 00:20, 18 September 2015