Ferment It Yourself

iGEM Paris-Bettencourt 2O15

Background	Aims	Results
Cobalamin (vitamin B12) deficiency is widely spread in India, due to diet that is mostly vegetarian.	We aimed at introducing a high-level cobalamin producer to the rice batter.	Tadaa.

Introduction

Vitamin B12, or cobalamin, is a family of molecules that are involved in only two chemical reactions in humans. However a cobalamin deficiency can lead to troubles related to nervous system, brain and formation of blood.

Ideas

Express the cobalamin biosynthesis pathway in Lactobacillus plantarum

Make Lactobacillus reuteri express a lot of cobalamin

Metabolic engineering

The pseudo-cobalamin problem

Use Propionibacterium freudenreichii

Advices for other teams

Conclusion

Click here to see our solution!

Team:Paris Bettencourt/Project/VitaminB12