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Revision as of 19:08, 12 September 2015
Short introduction
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Aliqua sausage turducken, reprehenderit culpa chicken capicola frankfurter spare ribs proident brisket porchetta. Bresaola in kevin corned beef, dolor aliquip consectetur. Porchetta pastrami beef ribs ex spare ribs pariatur corned beef alcatra kevin filet mignon laboris dolore jerky nulla. Cillum short ribs tongue laboris. Nulla adipisicing ut esse non ut veniam. Consectetur cupim jerky ullamco. Jerky brisket incididunt in.
Actual introduction
Aliqua xxdh001xx sausage turducken, reprehenderit culpa chicken capicola frankfurter spare ribs proident brisket porchetta. Bresaola in kevin corned beef, dolor aliquip consectetur. Porchetta pastrami beef ribs ex spare ribs pariatur corned beef alcatra kevin filet mignon laboris dolore jerky nulla. Cillum short ribs tongue laboris. Nulla adipisicing ut esse non ut veniam. Consectetur cupim jerky ullamco. Jerky brisket incididunt in. Turkey turducken dolor tempor tail, in sunt do kevin beef ribeye. Laborum frankfurter pig, consequat leberkas chicken drumstick ut short ribs. Pancetta magna voluptate sausage pork chop ut ipsum officia consectetur bresaola mollit beef ham hock quis deserunt. Sed magna sunt venison capicola boudin cow anim t-bone salami cupidatat kevin shoulder chuck. Landjaeger mollit swine, in meatball ut cupidatat sed jowl dolore tail laboris voluptate beef sirloin. Pork chop magna shoulder tempor pork. Pork chop tenderloin veniam venison pariatur nulla, ut quis sunt salami cupidatat adipisicing irure ribeye short ribs. Et do excepteur quis proident ipsum pork chop aliquip mollit prosciutto cow cillum. Turkey alcatra leberkas chicken ipsum dolor. Fugiat ea beef filet mignon tongue cow cupim ball tip voluptate eiusmod pork chop. Jerky leberkas boudin nostrud, ut ullamco aliqua frankfurter cupidatat pariatur labore.
Aliqua sausage turducken, reprehenderit culpa chicken capicola frankfurter spare ribs proident brisket porchetta. Bresaola in kevin corned beef, dolor aliquip consectetur. Porchetta pastrami beef ribs ex spare ribs pariatur corned beef alcatra kevin filet mignon laboris dolore jerky nulla. Cillum short ribs tongue laboris. Nulla adipisicing ut esse non ut veniam. Consectetur cupim jerky ullamco. Jerky brisket incididunt in. Turkey turducken dolor tempor tail, in sunt do kevin beef ribeye. Laborum frankfurter pig, consequat leberkas chicken drumstick ut short ribs. Pancetta magna voluptate sausage pork chop ut ipsum officia consectetur bresaola mollit beef ham hock quis deserunt. Sed magna sunt venison capicola boudin cow anim t-bone salami cupidatat kevin shoulder chuck. Landjaeger mollit swine, in meatball ut cupidatat sed jowl dolore tail laboris voluptate beef sirloin. Pork chop magna shoulder tempor pork. Pork chop tenderloin veniam venison pariatur nulla, ut quis sunt salami cupidatat adipisicing irure ribeye short ribs. Et do excepteur quis proident ipsum pork chop aliquip mollit prosciutto cow cillum. Turkey alcatra leberkas chicken ipsum dolor. Fugiat ea beef filet mignon tongue cow cupim ball tip voluptate eiusmod pork chop. Jerky leberkas boudin nostrud, ut ullamco aliqua frankfurter cupidatat pariatur labore.
Aliqua sausage turducken, reprehenderit culpa chicken capicola frankfurter spare ribs proident brisket porchetta. Bresaola in kevin corned beef, dolor aliquip consectetur. Porchetta pastrami beef ribs ex spare ribs pariatur corned beef alcatra kevin filet mignon laboris dolore jerky nulla. Cillum short ribs tongue laboris. Nulla adipisicing ut esse non ut veniam. Consectetur cupim jerky ullamco. Jerky brisket incididunt in. Turkey turducken dolor tempor tail, in sunt do kevin beef ribeye. Laborum frankfurter pig, consequat leberkas chicken drumstick ut short ribs. Pancetta magna voluptate sausage pork chop ut ipsum officia consectetur bresaola mollit beef ham hock quis deserunt. Sed magna sunt venison capicola boudin cow anim t-bone salami cupidatat kevin shoulder chuck. Landjaeger mollit swine, in meatball ut cupidatat sed jowl dolore tail laboris voluptate beef sirloin. Pork chop magna shoulder tempor pork. Pork chop tenderloin veniam venison pariatur nulla, ut quis sunt salami cupidatat adipisicing irure ribeye short ribs. Et do excepteur quis proident ipsum pork chop aliquip mollit prosciutto cow cillum. Turkey alcatra leberkas chicken ipsum dolor. Fugiat ea beef filet mignon tongue cow cupim ball tip voluptate eiusmod pork chop. Jerky leberkas boudin nostrud, ut ullamco aliqua frankfurter cupidatat pariatur labore. Aptabody
Short introduction
“The sea is everything. […] The sea is the vast reservoir of Nature. The globe began with sea, so to
speak”, Nemo said while the “Nautilus” was cruising with a school of hammerhead sharks deep
beneath the waves.
And the captain was right. Deep in the ocean billions of years ago the miracle of nature took place as
a pool of small molecules evolved to self-replicating lifeforms. The flagship role in this development
was probably taken by the most versatile class of molecules in the history of life: RNA.
Seemingly random nucleotides happened to be in the right order to form the first biocatalysts that
made life on the blue planet possible. Today we know those miracles of nature as ribozymes. Inspired
by this, humanity took evolution into their own hands to create aptamers – nucleic acids capable of
encaging molecules. This allows for the detection of virtually anything. Still this process has been
tedious and time consuming much like fishing with a rod in an ocean. We want to revolutionize this
former evolutionary process and want to make it swift like a shark tracking down its prey.
Yet to really bring out the strengths of these simple yet powerful molecules just comprised of A, U, C
and G we want to combine aptamers and ribozymes to create a toolset for the synthetic biologist to
create allosteric ribozymes able to sense a variety of molecules. Therefore, we hope to introduce the
true origins of life and the capabilities of functional RNA to iGEM.
Join us as we sail forth into new
waters of synthetic biology.
Further content
Supporting iGEM Team Paris Bettencourt
iGEM Paris Bettencourt has set up a visual databse that should help various iGEM teams collaborate and find common ground. In that database all teams can enter techniques, keywords, organism and many more thev are knowdledgeable in or have been working on. As common dots are connected automatically, it's easy so see, whom to ask for a collaboration.
Though we came a little late to the party, we really loved the idea and hoped, that the database has helped various teams!
"Rhizi is an open-sourced web of knowledge where nodes are sources of information (e.g. scientific articles, questions, blog posts) and edges are the links between them. The goal of Rhizi is to create information rich links between knowledge, open questions and ideas, through encouraging users to vote, comment, and create new relationships."
Collecting impressions from the community
It’s done. We’ve finally decided upon a logo. It’s beautiful, it’s blue, it’s fishy *wink*. The next step was to choose a color scheme and a general style for the wiki. As we feared that our own ideas might be too similar we thought of asking a broader public how they would design a website based on our logo. In order to do so, we headed to the ’Neckarwiese’. During summer, a big part of Heidelbergs population decideds to go there and enjoy the sun, have a BBQ or just relax – so we caught them off guard.
We have had prepared a little presentatio with which we introduced them to iGEM and Synthetic Biology. Afterwards we explained them what we planned on doing, showed them our logo and asked, how they would design a website, based on what they’ve just heard. The general consens was to go for a blue theme, maybe add a little algae green and generally stick to maritime iconography. Unexpectedly we actually met someone who knew his stuff: Natalie, a student of the history of arts from Berlin. She gave us useful advice on how play with the different colors, what to avoid and even added a little touch of history to it. Lucky catch!
With fresh ideas we headed back to the lab and continued our experiments, being envious of all the people that could continue to sleep in the sun.
plasmid.js - Interactive plasmids
It is always cubersome to create vector maps, and then putting the static images on the web. We thought it would be a lot more fun to just autogenerate interactive plasmids dynamically from data. That's why we wrote plasmid.js, a JavaScript library to generate interactive vector maps for web pages.
Why should you use it?
It is dead simple to use!
The includes
<script src="jquery.js" type="text/javascript" charset="utf-8"></script> <scripr src="raphael.js" type="text/javascript" charset="utf-8"></script> <script src="plasmid.js" type="text/javascript" charset="utf-8"></script>
The placeholders
<div id="canvas"></div> <div id="info"></div>or, if you are working with an iGEM wiki
{{Heidelberg/js/plasmid.js}}The JavaScript
$(function() {
// You could also load your data via AJAX
var inserts = [
{
size: 40, // Size in angles! (there are 360 of them available)
color: "#0F0", // You can use any valid css format
label: "GFP", // The label to display in the legend
description: "Green Fluorescent Protein", // The description to put in the infobox
gap: false, // If not given this defaults to true
promoter: true // This is a promoter, defaults to false
},
{
size: 10,
color: "#F00",
label: "Brow Fox",
description: "He likes jumping over dogs.",
gap: true
},
{
size: 46,
color: "#00F",
label: "Lazy Dog",
description: "He likes beeing jumpt over."
},
{
size: 19,
color: "#0FF",
label: "Short one",
description: "Wirklich, Wirklich kurz nun auch wieder nicht.",
promoter: true
},
{
size: 1,
color: "#FF0",
label: "Even shorter one",
description: "Und knackig",
gap: false,
promoter: true
}];
// Required parameters are: id of the canvas, id of the infobox,
// the inserts and the diameter of the plasmid. Note, that there
// is spacing and a legend added (default: width + 575, height + 50)
// These values can be changed easily, see below.
var plasmid = new Plasmid('canvas', 'info', inserts, 500);
plasmid.draw();
});
Plus, it also looks great!
Further options
There are two ways to specify optional settings; you can either pass them via the constructor or set the corresponding attributes after the object is created (it's JavaScript, ...). Below you can see a annotated version of the constructor.
function Plasmid(canvas, infobox, inserts, diameter, legendWidth, insertWidth, defaultText, insertBoxAttr, fontSize, spacing, startAngle) {
// Are all required parameters given?
// [...]
this.canvas = canvas; // The id of the canvas placeholder div
this.inserts = inserts; // The array whith the given inserts (see above)
this.diameter = diameter; // The diameter of the plasmid, this is *not* the size of the canvas
this.infobox = infobox; // The id of the infobox to put the descriptions in
// Set sane defaults for optional parameters
this.legendWidth = legendWidth || 500; // The width of the legend
this.radiusOfInsertBox = insertWidth || diameter / 13; // how "thick" the boxes of the inserts are drawn
this.defaultText = defaultText || "Hover over an insert to get more information!"; // default text in infobox
this.fontSize = fontSize || 20; // The font size for legend entries
this.spacing = spacing || 25; // spacing is the number of pixels put above and below the plasmid and left to the legend
this.startAngle = startAngle || -40; // The angle at which the first plasmid starts
this.insertBoxAttr = insertBoxAttr || { // The attributes to set on the boxes representing an insert
stroke: "#666",
opacity: 0.7,
"stroke-width": 1,
"stroke-linejoin": "round"
};
// [...]
}