Difference between revisions of "Team:Heidelberg/Description"

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{{Heidelberg/Header}}
 
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                        <h3 class="basicheader"> Improvement of a Part </h3>
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One of the main strengths of synthetic biology, compared to other scientific disciplines is the strong community it is build upon. Yet this community is nothing without active participation and interaction. We therefore see it as a very important responsibility of all iGEM-teams to constantly improve and newly apply parts submitted to the registry. As we were working with functional nucleotides, we soon took notice of BBa_K1330000, better known as Spinach2.1 from DTU Denmark iGEM team 2014. This modified version of Spinach2 was made compatible with the RFC 10 standard without change of functionality.
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Envisionning the introduction of the power of aptamers and aptazymes to the iGEM community, we improved part BBa_K1330000 by making it depending on and thereby capable of sensing ATP - we call it BBa_K1614019. We show a possible application of this improved part in the optimization of <i>in vitro</i> transcription conditions and furthermore enhance the readout and the activity by software engineering. Besides, one could imagine sensing other small molecules in a standardized way.
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Revision as of 03:04, 19 September 2015

Improvement of a Part

One of the main strengths of synthetic biology, compared to other scientific disciplines is the strong community it is build upon. Yet this community is nothing without active participation and interaction. We therefore see it as a very important responsibility of all iGEM-teams to constantly improve and newly apply parts submitted to the registry. As we were working with functional nucleotides, we soon took notice of BBa_K1330000, better known as Spinach2.1 from DTU Denmark iGEM team 2014. This modified version of Spinach2 was made compatible with the RFC 10 standard without change of functionality.

Envisionning the introduction of the power of aptamers and aptazymes to the iGEM community, we improved part BBa_K1330000 by making it depending on and thereby capable of sensing ATP - we call it BBa_K1614019. We show a possible application of this improved part in the optimization of in vitro transcription conditions and furthermore enhance the readout and the activity by software engineering. Besides, one could imagine sensing other small molecules in a standardized way.