Difference between revisions of "Team:Cambridge-JIC/Description"

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<h2> Project Description </h2>
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<p>Tell us about your project, describe what moves you and why this is something important for your team.</p>
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            <h1>Overview</h1>
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The ability to image fluorescent stains and proteins is integral to modern biology, but the necessary equipment can be prohibitively expensive, particularly for schools and labs in developing countries. To address this issue, we aim to provide an affordable and well documented fluorescence microscope - easy to build and modify.<br>
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<h5>What should this page contain?</h5>
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The mechanics of our microscope will be 3D printable, and all other parts will be cheap and easy to source. The figure below shows our basic set-up: the sensor and fluorescence cube will move in the Z direction to achieve the necessary focus, whilst the sample will move in the X and Y directions (in order to achieve this translation, we will use Dr Richard Bowman's innovative method, which exploits the flexibility of the 3D printed parts).<br>
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<li> A clear and concise description of your project.</li>
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<li>A detailed explanation of why your team chose to work on this particular project.</li>
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<img src="https://static.igem.org/mediawiki/2015/f/f6/CamJIC-microscope.png" width="500px">
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<li>References and sources to document your research.</li>
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As proof-of-concept, we will develop a fluorescent cube for wild-type GFP and one for RFP. They will be interchangeable as necessary, and can be removed for bright-field imaging. Ultimately, we aim to achieve < 10 micron resolution, both in bright-field and fluorescent modes. We are also developing user-friendly software to control the microscope and automate image processing.<br>
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We believe that everyone should have access to good education and facilities, regardless of financial status: this is why we want to bring you the best possible low-cost microscope.
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<h4>Advice on writing your Project Description</h4>
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We encourage you to put up a lot of information and content on your wiki, but we also encourage you to include summaries as much as possible. If you think of the sections in your project description as the sections in a publication, you should try to be consist, accurate and unambiguous in your achievements.  
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Judges like to read your wiki and know exactly what you have achieved. This is how you should think about these sections; from the point of view of the judge evaluating you at the end of the year.
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<p>iGEM teams are encouraged to record references you use during the course of your research. They should be posted somewhere on your wiki so that judges and other visitors can see how you though about your project and what works inspired you.</p>
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<h4>Inspiration</h4>
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<p>See how other teams have described and presented their projects: </p>
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<li><a href="https://2014.igem.org/Team:Imperial/Project"> Imperial</a></li>
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<li><a href="https://2014.igem.org/Team:UC_Davis/Project_Overview"> UC Davis</a></li>
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<li><a href="https://2014.igem.org/Team:SYSU-Software/Overview">SYSU Software</a></li>
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Revision as of 15:33, 22 July 2015

CAMBRIDGE-JIC

Overview

The ability to image fluorescent stains and proteins is integral to modern biology, but the necessary equipment can be prohibitively expensive, particularly for schools and labs in developing countries. To address this issue, we aim to provide an affordable and well documented fluorescence microscope - easy to build and modify.

The mechanics of our microscope will be 3D printable, and all other parts will be cheap and easy to source. The figure below shows our basic set-up: the sensor and fluorescence cube will move in the Z direction to achieve the necessary focus, whilst the sample will move in the X and Y directions (in order to achieve this translation, we will use Dr Richard Bowman's innovative method, which exploits the flexibility of the 3D printed parts).



As proof-of-concept, we will develop a fluorescent cube for wild-type GFP and one for RFP. They will be interchangeable as necessary, and can be removed for bright-field imaging. Ultimately, we aim to achieve < 10 micron resolution, both in bright-field and fluorescent modes. We are also developing user-friendly software to control the microscope and automate image processing.

We believe that everyone should have access to good education and facilities, regardless of financial status: this is why we want to bring you the best possible low-cost microscope.