Difference between revisions of "Team:UCSF/Project Sub"

 
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<div class="main-container">
 
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   <div id="navProject1" class="navSub">
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   <div class="navSub navProject">
 
   <a id="pageDescription"></a>
 
   <a id="pageDescription"></a>
  
 
     <ul>
 
     <ul>
  
         <li id = "projectDescription"><p>DESCRIPTION</p>
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         <li class = "projectDescriptionP"><p>DESCRIPTION</p>
 
         </li>
 
         </li>
  
         <li id = "projectDesign"><a href="#pageDesign">DESIGN</a>
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         <li class = "projectModeling down"><a href="#pageModeling">MODELING</a>
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        </li>
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        <li class = "projectResults down"><a href="#pageResults">RESULTS</a>
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        </li>
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        <li class = "projectParts down"><a href="#pageParts">PARTS</a>
 
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   <div class="main-content">
 
   <div class="main-content">
  
     <h1 class="Header">DESCRIPTION</h1>
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     <p class="headerProject">DESCRIPTION</p>
  
     <p class="content1">Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here. Pictures here.  
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     <div class="headerBreak"></div>
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<div class="circuitCenter" style="height:250px">
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<img src="https://static.igem.org/mediawiki/2015/e/ef/UCSF_Generalized_Circuit_Diagram.png" alt="General Circuit Diagram" width="431" height="250" style="margin:0 0 0 215px;">
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</div>
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    <p class="content1">We are building a synthetic model in <i>S. cerevisiae</i> to understand communication's role in biological decision-making. Our model consists of four main parts: Basic Circuit, Positive Feedback, Signal Degradation, and Clustering. Using the model, we hope to be able to cause a population divergence with an outside stimulus.
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    </p>
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    <p class="content2">To learn more about our synthetic model, click the button below.
 
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     </p>
 
      
 
      
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   <a id="pageModeling"></a>
  
 
     <ul>
 
     <ul>
  
         <li id = "projectDescription2"><a href="#pageDescription">DESCRIPTION</a>
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         <li class = "projectDescription up"><a href="#pageDescription">DESCRIPTION</a>
 
         </li>
 
         </li>
  
         <li id = "projectDesign2"><p>DESIGN</p>
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         <li class = "projectModelingP"><p>MODELING</p>
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        </li>
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        <li class = "projectResults down"><a href="#pageResults">RESULTS</a>
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        <li class = "projectParts down"><a href="#pageParts">PARTS</a>
 
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   <div class="main-content">
 
   <div class="main-content">
  
     <h1 class="Header">ATTRIBUTIONS</h1>
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     <p class="headerProject">MODELING</p>
  
     <p class="content1">Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.Stuff goes here.
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    <div class="headerBreak"></div>
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     <p class="content1">
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Our project this year is centered around the emergence of distinct community phenotypes when individuals in a population are allowed to communicate. Focusing on the community phenotype of bimodal activation, our model aims to mathematically estimate distinct states of multiple cells in the population in different immediate extracellular environments.
 
     </p>
 
     </p>
  
     <div class="readMore"><a href="https://2015.igem.org/Team:UCSF/Attributions">Read More <img class="readMoreArrow" src="https://static.igem.org/mediawiki/2015/6/68/UCSF_Read_More_Arrow.png" alt="Next Arrow" height="35" width="35"></a>
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    <p class="content2">
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For more information on our modeling, click the button below.
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    </p>
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     <div class="readMore"><a href="https://2015.igem.org/Team:UCSF/Modeling">Read More <img class="readMoreArrow" src="https://static.igem.org/mediawiki/2015/6/68/UCSF_Read_More_Arrow.png" alt="Next Arrow" height="35" width="35"></a>
 
     </div>
 
     </div>
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  </div>
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  <div class="navSub navProject">
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  <a id="pageResults"></a>
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    <ul>
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        <li class = "projectDescription up"><a href="#pageDescription">DESCRIPTION</a>
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        </li>
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        <li class = "projectModeling up"><a href="#pageModeling">MODELING</a>
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        </li>
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        <li class = "projectResultsP"><p>RESULTS</p>
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        </li>
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        <li class = "projectParts down"><a href="#pageParts">PARTS</a>
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      </ul>
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  </div>
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  <div class="main-content">
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    <p class="headerProject">RESULTS</p>
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    <div class="headerBreak"></div>
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    <p class="content1">
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Our goal for our circuit is to elicit a divergent community response from two genetically similar cells by varying different communication parameters. To measure distinct community responses in our circuit, we will look at INDIVIDUAL (GFP) response versus COMMUNITY (RFP) response.
 +
    </p>
 +
 +
    <p class="content2">To learn more about our experiments and results, click the button below.
 +
    </p>
 +
 +
    <div class="readMore"><a href="https://2015.igem.org/Team:UCSF/Results">Read More <img class="readMoreArrow" src="https://static.igem.org/mediawiki/2015/6/68/UCSF_Read_More_Arrow.png" alt="Next Arrow" height="35" width="35"></a>
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    </div>
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  </div>
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  <div class="navSub navProject">
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  <a id="pageParts"></a>
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    <ul>
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        <li class = "projectDescription up"><a href="#pageDescription">DESCRIPTION</a>
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        </li>
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        <li class = "projectModeling up"><a href="#pageModeling">MODELING</a>
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        </li>
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        <li class = "projectResults up"><a href="#pageResults">RESULTS</a>
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        </li>
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        <li class = "projectPartsP"><p>PARTS</p>
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      </ul>
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  </div>
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  <div class="main-content">
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    <p class="headerProject">PARTS</p>
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    <div class="headerBreak"></div>
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    <p class="content1">
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Our project consisted of different promoters, fluorescent proteins, and many other parts that contributed to our overall circuit. We are making many of these parts available to the public by submitting them to the parts registry. Our team has worked painstakingly throughout the final weeks of the summer to adapt our parts to be BioBrick compatible. By ordering our parts you can recreate 2015 UCSF iGEM project by constructing our circuit.
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    </p>
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    <div class="readMore"><a href="https://2015.igem.org/Team:UCSF/Parts">Read More <img class="readMoreArrow" src="https://static.igem.org/mediawiki/2015/6/68/UCSF_Read_More_Arrow.png" alt="Next Arrow" height="35" width="35"></a>
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          <div id="backToTop"><a style="text-decoration:none" id="Top">
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            <img id="backToTopArrow" src="https://static.igem.org/mediawiki/2015/6/68/UCSF_Read_More_Arrow.png" alt="Back To Top Arrow" width="90" height="90">
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            </br>
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            <p>BACK TO TOP</p></a>
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          </div>
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          <div id="siteMap">
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            <ul>
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              <h3 class="hoverHome"><a href="https://2015.igem.org/Team:UCSF">HOME</a></h3>
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            </ul>
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            <ul id="hoverProjectSections">
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              <h3 class="hoverProject"><a href="https://2015.igem.org/Team:UCSF/Project_Sub">PROJECT</a></h3>
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              <li><a href="https://2015.igem.org/Team:UCSF/Description">DESCRIPTION</a></li>
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              <li><a href="https://2015.igem.org/Team:UCSF/Modeling">MODELING</a></li>
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              <li><a href="https://2015.igem.org/Team:UCSF/Results">RESULTS</a></li>
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              <li><a href="https://2015.igem.org/Team:UCSF/Parts">PARTS</a></li>
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            </ul>
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            <ul id="hoverJudgingSections">
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              <h3 class="hoverJudging"><a href="https://2015.igem.org/Team:UCSF/Judging_Sub">JUDGING</a></h3>
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              <li><a href="https://2015.igem.org/Team:UCSF/Medal_Requirements">MEDAL</br>REQUIREMENTS</a></li>
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              <li><a href="https://2015.igem.org/Team:UCSF/Safety">SAFETY</a></li>
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            </ul>
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              <h3 class="hoverHumanPractices"><a href="https://2015.igem.org/Team:UCSF/Human_Practices_Sub">HUMAN PRACTICES</a></h3>
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              <li><a href="https://2015.igem.org/Team:UCSF/Practices">HUMAN PRACTICES</a></li>
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              <li><a href="https://2015.igem.org/Team:UCSF/Wiki_Flicks">WIKI FLICKS</a></li>
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              <li><a href="https://2015.igem.org/Team:UCSF/Collaborations">COLLABORATIONS</a></li>
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              <h3 class="hoverNotebooks"><a href="https://2015.igem.org/Team:UCSF/Notebook_Sub">NOTEBOOKS</a></h3>
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              <li><a href="https://2015.igem.org/Team:UCSF/Notebook">NOTEBOOKS</a></li>
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              <li><a href="https://2015.igem.org/Team:UCSF/Protocols">PROTOCOLS</a></li>
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              <h3 class="hoverTeam"><a href="https://2015.igem.org/Team:UCSF/Team_Sub">TEAM</a></h3>
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              <li><a href="https://2015.igem.org/Team:UCSF/Attributions">ATTRIBUTIONS</a></li>
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              <li><a href="mailto:syssynbio@ucsf.edu"><img src="https://static.igem.org/mediawiki/2015/8/82/Email_Logo.png" alt="Email Logo" width="30" height="30"> syssynbio@ucsf.edu</a></li>
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Latest revision as of 02:22, 19 September 2015

DESCRIPTION

General Circuit Diagram

We are building a synthetic model in S. cerevisiae to understand communication's role in biological decision-making. Our model consists of four main parts: Basic Circuit, Positive Feedback, Signal Degradation, and Clustering. Using the model, we hope to be able to cause a population divergence with an outside stimulus.

To learn more about our synthetic model, click the button below.

MODELING

Our project this year is centered around the emergence of distinct community phenotypes when individuals in a population are allowed to communicate. Focusing on the community phenotype of bimodal activation, our model aims to mathematically estimate distinct states of multiple cells in the population in different immediate extracellular environments.

For more information on our modeling, click the button below.

RESULTS

Our goal for our circuit is to elicit a divergent community response from two genetically similar cells by varying different communication parameters. To measure distinct community responses in our circuit, we will look at INDIVIDUAL (GFP) response versus COMMUNITY (RFP) response.

To learn more about our experiments and results, click the button below.

PARTS

Our project consisted of different promoters, fluorescent proteins, and many other parts that contributed to our overall circuit. We are making many of these parts available to the public by submitting them to the parts registry. Our team has worked painstakingly throughout the final weeks of the summer to adapt our parts to be BioBrick compatible. By ordering our parts you can recreate 2015 UCSF iGEM project by constructing our circuit.